How T cells combat tuberculosis
By tracking T cell activity, researchers uncover promising tuberculosis vaccine and drug targets
Tuberculosis
The aim of this work, in collaboration with Dr. Bjoern Peters, is to identify and characterize T cell epitopes from
Lindestam Arlehamn Lab
Cecilia Lindestam Arlehamn,
Ph.D.
Research Assistant Professor
Center for Autoimmunity and Inflammation, Center for Sex-based Differences in the Immune System, Center for Vaccine Innovation
My laboratory is focused on understanding T cell immune responses to Mycobacterium tuberculosis and other infections, as well as self-antigens
Once upon a BCG vaccine
LA JOLLA—A long, long time ago, the BCG vaccine was approved for use against tuberculosis (TB), and it’s still
New vaccine ingredient shows promise
Most vaccines include particles called adjuvants. But not all adjuvants are created equal.
Tuberculosis
T cell responses to Mycobacterium tuberculosis infection and vaccination: Following completion of a massive epitope discovery effort (also supported by
Tuberculosis
Investigation of human immune signatures of latent MTB infection, active disease and BCG vaccination. (NIH/NIAID, U19 AI118626) Proteome-wide characterization of
Sette Lab
Alessandro Sette,
Dr.Biol.Sci.
Professor
Center for Autoimmunity and Inflammation - Director, Center for Cancer Immunotherapy, Center for Vaccine Innovation
Alessandro Sette, Dr.Biol.Sci., defines in chemical terms the specific structures (epitopes) that the immune system recognizes and uses this knowledge to measure and understand immune responses.
No cell is an island
LA JOLLA, CA – Sorting through individual immune cells is a handy way to see how the body responds to
Immunoprofiling
The composition of an immune system varies not just from person to person, but over time—shifting as our health changes,
Mapping T cells
An international team led by LJI investigator Alessandro Sette, Dr. Biol. Sci., characterizes the immune response to dengue virus and
La Jolla Institute for Immunology team receives $18 million consortium grant
LA JOLLA, CA – The La Jolla Institute for Immunology (LJI) is pleased to announce that an international team led