Research Areas

Research Areas

Our focus is immunology, because we believe that no other biomedical discipline has greater implications for human health than immunology. By unraveling the complexities of the immune system, LJI researchers are directly tackling an extraordinarily diverse array of diseases, which together account for more than two-thirds of all deaths in the U.S. each year. Such diseases include type 1 and type 2 diabetes, cancer, rheumatoid arthritis, multiple sclerosis, asthma, allergies, influenza, dengue fever and many other illnesses.

From The Lab

Apr 17, 2020 // Nature Communications

LJI Scientists Link Immune Cells to Parkinson’s Disease Onset

New research gives further evidence that autoimmunity plays a role in Parkinson’s disease
Apr 7, 2020 // Cell Reports

Too Much Haste Leads to Little Speed

A Newly Discovered Biological Switch Evolved to Stimulate the Immune System can also Lead to Immune Paralysis
Mar 30, 2020 // San Diego Union Tribune

San Diego virus fighter to lead international effort to stanch spread of coronavirus

Erica Ollmann Saphire will direct the team from her lab at the La Jolla Institute
Mar 23, 2020 // Washington Post

The coronavirus isn’t alive. That’s why it’s so hard to kill.

The science behind what makes this coronavirus so sneaky, deadly and difficult to defeat
Dec 24, 2019

Cellular culprit suspected of pushing dengue fever from bad to worse is cleared using advanced transcriptomics

The finding is important to both the basic understanding of this disease—the world’s most common mosquito-borne illness—and to the hunt for an effective vaccine for dengue.