Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type-dependent effects of disease-risk variants

Feb 25, 2022 Sci Immunol

Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type-dependent effects of disease-risk variants

Schmiedel BJ, Gonzalez-Colin C, Fajardo V, Rocha J, Madrigal A, Ramírez-Suástegui C, Bhattacharyya S, Simon H, Greenbaum JA, Peters B, Seumois G, Ay F, Chandra V, Vijayanand P

Feb 4, 2022 J Cell Biol

Pluriptency exit is guided by the Peln1-mediated disruption of intrachromosomal architecture

Wang Y, Jia L, Wang C, Du Z, Zhang S, Zhou L, Wen X, Li H, Chen H, Nie Y, Li D, Liu S, Figueroa DS, Ay F, Xu W, Zhang S, Li W, Cui J, Hoffman AR, Guo H, Hu JF

Apr 4, 2022 Nature

Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs.

Eschweiler S, Ramírez-Suástegui C, Li Y, King E, Chudley L, Thomas J, Wood O, von Witzleben A, Jeffrey D, McCann K, Simon H, Mondal M, Wang A, Dicker M, Lopez-Guadamillas E, Chou TF, Dobbs NA, Essame L, Acton G, Kelly F, Halbert G, Sacco JJ, Schache AG, Shaw R, McCaul JA, Paterson C, Davies JH, Brennan PA, Singh RP, Loadman PM, Wilson W, Hackshaw A, Seumois G, Okkenhaug K, Thomas GJ, Jones TM, Ay F, Friberg G, Kronenberg M, Vanhaesebroeck B, Vijayanand P, Ottensmeier CH

Oct 17, 2022 Immune Matters

Get to know Ferhat Ay, Ph.D., the chromosome cartographer

How computational biology is propelling the field of immunology

Feb 25, 2022 Science Immunology

Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type–dependent effects of disease-risk variants

Benjamin J. Schmiedel,vCristian Gonzalez-Colin, Vicente Fajardo, Job Rocha, Ariel Madrigal, Ciro Ramirez-Suastegui, Sourya Bhattacharyya, Hayley Simon, Jason A. Greenbaum, Bjoern Peters, Gregory Seumois, Ferhat Ay, Vivek Chandra, Pandurangan, Vijayanand

Jan 1, 2021 Nat Genet.

Promoter-interacting expression quantitative trait loci are enriched for functional genetic variants.

Chandra V, Bhattacharyya S, Schmiedel BJ, Madrigal A, Gonzalez-Colin C, Fotsing S, Crinklaw A, Seumois G, Mohammadi P, Kronenberg M, Peters B, Ay F, Vijayanand P.

Jan 21, 2021 Sci Immunol.

Severely ill COVID-19 patients display impaired exhaustion features in SARS-CoV-2-reactive CD8+ T cells.

Kusnadi A, Ramírez-Suástegui C, Fajardo V, Chee SJ, Meckiff BJ, Simon H, Pelosi E, Seumois G, Ay F, Vijayanand P, Ottensmeier CH.

Apr 1, 2021 Genome Res.

Multi-cell type gene coexpression network analysis reveals coordinated interferon response and cross-cell type correlations in systemic lupus erythematosus.

Panwar B, Schmiedel BJ, Liang S, White B, Rodriguez E, Kalunian K, McKnight AJ, Soloff R, Seumois G, Vijayanand P, Ay F

Mar 30, 2021 J Health Popul Nutr.

A comparison of the different anthropometric indices for assessing malnutrition among older people in Turkey: a large population-based screening.

Başıbüyük GÖ, Ayremlou P, Saeidlou SN, Ay F, Dalkıran A, Simzari W, Vitályos GÁ, Bektaş Y.

Mar 15, 2021 Development.

Sox2-Evf2 lncRNA-mediated mechanisms of chromosome topological control in developing forebrain.

Cajigas I, Chakraborty A, Lynam M, Swyter KR, Bastidas M, Collens L, Luo H, Ay F, Kohtz JD.

May 20, 2021 Bioinformatics.

ExTraMapper: Exon- and Transcript-level mappings for orthologous gene pairs.

Chakraborty A, Ay F, Davuluri RV.

May 1, 2021 Genome Res.

Third-generation sequencing revises the molecular karyotype for Toxoplasma gondii and identifies emerging copy number variants in sexual recombinants.

Xia J, Venkat A, Bainbridge RE, Reese ML, Le Roch KG, Ay F, Boyle JP.