HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.
Regulation of mucosal immunity by stromal cells and dendritic cells crosstalk in the gut
Genetic regulation by vitamin A is involved in multiple biological processes such as embryonic development, vision, and immunity. To exert
The Contribution of Central and/or Peripheral Tolerance in Celiac Disease
Celiac Disease (CD) is an autoimmune-like inflammatory disease induced by aberrant immune responses initiated by MHC class II restricted CD4
Mucosal CD4- CD8- T Cells
One large subgroup of specialized T cells is encompassed by the intraepithelial T cells which are located in the epithelium
Role of Pre-TCR Signaling in Central Tolerance and Autoimmunity?
Autoimmunity is a self-destructive disease condition mediated mainly by pathogenic selfreactive αβ T cell receptor (TCR) expressing T lymphocytes. Self-tolerance
Mechanisms Involved in The Generation of High Affinity Effector Memory T Cells
A hallmark of immune memory is that repeated infections are met with accelerated or/and enhanced protective immunity. Furthermore, unlike naive
CD4+ Cytotoxic Lymphocytes
MHC class-II restricted CD4+ T cytotoxic cells (CD4 CTL) are among the best examples of extreme measures the immune system
T Cell Function
We are now trying to elucidate the regulatory functions displayed by the self-specific agonist selected T cells and their role
One large subgroup of these specialized T cells is encompassed by the IEL which are located in the epithelium of