LJI scientists solve the mystery of why OGT enzyme is critical for cell survival

Jan 11, 2023 Research News

LJI scientists solve the mystery of why OGT enzyme is critical for cell survival

LA JOLLA, CA — Researchers at La Jolla Institute for Immunology (LJI) have at last uncovered how an enzyme called

Jan 14, 2022 Blood

A Congenital Anemia Reveals Distinct Targeting Mechanisms for Master Transcription Factor GATA1.

Ludwig L, Lareau CA, Bao EL, Liu N, Utsugisawa T, Tseng AM, Myers SA, Verboon JM, Ulirsch JC, Luo W, Muus C, Fiorini C, Olive ME, Vockley CM, Munschauer M, Hunter A, Ogura H, Yamamoto T, Inada H, Nakagawa S, Ozono S, Subramanian V, Chiarle R, Glader B, Carr SA, Aryee MJ, Kundaje A, Orkin S, Regev A, McCavit T, Kanno H, Sankaran VG.

Mar 16, 2022 Nucleic Acids Res.

Retron reverse transcriptase termination and phage defense are dependent on host RNase H1.

Palka C, Fishman CB, Bhattarai-Kline S, Myers SA, Shipman SL.

Feb 1, 2022 Curr Opin Immunol.

Mechanisms encoding STAT functional diversity for context-specific inflammatory responses.

Myers SA, Gottschalk RA

Jan 1, 2022 Nat Immunol.

Identification of RIOK2 as a master regulator of human blood cell development.

Ghosh S, Raundhal M, Myers SA, Carr SA, Chen X, Petsko GA, Glimcher LH.

Feb 1, 2022 Cur Opin Immunol.

Mechanisms encoding STAT functional diversity for context-specific inflammatory responses.

Myers SA, Gottschalk RA.

Jan 1, 2022 Nat Immunol.

Identification of RIOK2 as a master regulator of human blood cell development.

Ghosh S, Raundhal M, Myers SA, Carr SA, Chen X, Petsko GA, Glimcher LH.

Jan 14, 2022 Blood.

A congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.

Jan 1, 2021 Mol Cell Proteomics.

Novel antibodies for the simple and efficient enrichment of native O-GlcNAc modified peptides.

Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA.

Apr 1, 2021 Nat Immunol.

Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias.

Raundhal M, Shrestha G, Myers SA, Cuoco MS, Meromit S, Carr SA, Waikar SS, Bonventre JV, Ritz J, Stone RM, Steensma DP, Regev A, Glimcher LH.

Aug 17, 2021 Nat Commun.

Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery.

Qin W, Myers SA, Carey DK, Carr SA, Ting AY.

Mar 8, 2016 Elife

SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells

Myers SA, Peddada S, Chatterjee N, Friedrich T, Tomoda K, Krings G, Thomas S, Maynard J, Broeker M, Thomson M, Pollard K, Yamanaka S, Burlingame AL, Panning B.