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Aug 25, 2021 Cell Res

Novel Attempts Launched Toward Universal Sarbecovirus Vaccine

Li H, Saphire EO

Sep 23, 2021 Science

Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study

Hastie KM, Li H, Bedinger D, Schendel SL, Dennison SM, Li K, Rayaprolu V, Yu X, Mann C, Zandonatti M, Diaz Avalos R, Zyla D, Buck T, Hui S, Shaffer K, Hariharan C, Yin J, Olmedillas E, Enriquez A, Parekh D, Abraha M, Feeney E, Horn GQ; CoVIC-DB team1, Aldon Y, Ali H, Aracic S, Cobb RR, Federman RS, Fernandez JM, Glanville J, Green R, Grigoryan G, Lujan Hernandez AG, Ho DD, Huang KA, Ingraham J, Jiang W, Kellam P, Kim C, Kim M, Kim HM, Kong C, Krebs SJ, Lan F, Lang G, Lee S, Leung CL, Liu J, Lu Y, MacCamy A, McGuire AT, Palser AL, Rabbitts TH, Rikhtegaran Tehrani Z, Sajadi MM, Sanders RW, Sato AK, Schweizer L, Seo J, Shen B, Snitselaar JJ, Stamatatos L, Tan Y, Tomic MT, van Gils MJ, Youssef S, Yu J, Yuan TZ, Zhang Q, Peters B, Tomaras GD, Germann T, Saphire EO

Oct 21, 2021 Research News

Erica Ollmann Saphire receives $2.6 million grant to collaborate on pan-coronavirus vaccine

La Jolla Institute scientists team up with Brigham and Women's Hospital to guide the development of vaccines against the coronavirus family

Oct 20, 2021 Immune Matters

Erica Ollmann Saphire takes the helm

See a problem, take action. That’s how she was raised

Oct 20, 2021 Immune Matters

How I see LJI

A letter from President and CEO Erica Ollmann Saphire, Ph.D.

Oct 11, 2021 Research News

Lungs of COVID-19 survivors teem with virus-fighting ‘memory’ cells

Even elderly survivors show a strong, persistent immune memory

Sep 23, 2021 Research News

From Alpha to Epsilon: Consortium study illuminates surfaces of Spike most resistant to antibody escape

LJI-led Coronavirus Immunotherapeutic Consortium identifies antibody 'communities' with power to stop SARS-CoV-2 variants

Apr 13, 2021 Immunity

A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus

Gunn BM, Lu R, Slein MD, Ilinykh PA, Huang K, Atyeao C, Shcendel SL, Kim J, Cain C, Roy V, Suscovich TJ, Takada A, Halfmann PJ, Kawaoka Y, Pauthner MG, Momoh M, Goba A, Kanneh L, Andersen KG, Schieffelin JS, Grant D, Garry RF, Saphire EO, Bukreyev A, Alter G

Apr 13, 2021 Cell Rep

Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form

Landeras-Bueno S, Wasserman H, Oliveira G, VanAernum Z, Busch F, Salie ZL, Wysocki VH, Andersen K, Saphire EO

Jan 28, 2021 Nat Struct Mol Biol

Structural biology in the fight against COVID-19

Barcena M, Barnes CO, Beck M, Bjorkman PJ, Canard B, Gao GF, Gao Y, Hilgenfeld R, Hummer G, Patwardhan A, Santoni G, Saphire EO, Schaffitzel C, Schendel SL, Smith JL, Thorn A, Veesler D, Zhang P, Zhou Q

Feb 3, 2021 J Virol.

Prominent Neutralizing Antibody Response Targeting the Ebolavirus Glycoprotein Subunit Interface Elicited by Immunization

Wang Y, Howell KA, Brannan J, Aganas KN, Turner HL, Wirchnianski AS, Kailasan S, Fusco M, Galkin A, Chiang C, Zhao X, Saphire EO, Chandran K, Ward AB, Dye JM, Aman MJ, Geisbert TW, Li Y

Feb 4, 2020 Plos Pathog

Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry

Schafer A, Xiong R, Cooper L, Nowar R, Lee H, Li Y, Ramirez BE, Peet NP, Caffrey M, Thatcher GRJ, Saphire EO, Cheng H, Rong L