New insights into the role of autoreactive CD8 T cells and cytokines in human type 1 diabetes.

Jan 5, 2021 Front Endocrinol (Lausanne).

New insights into the role of autoreactive CD8 T cells and cytokines in human type 1 diabetes.

Bender C, Rajendran S, von Herrath MG.

Jan 1, 2021 J Autoimmun.

The effect of Toll-like receptor stimulation on the motility of regulatory T cells.

Chodaczek G, Pagni PP, Christoffersson G, Ratliff SS, Toporkiewicz M, Wegrzyn AS, von Herrath M.

Mar 1, 2021 Diabetes.

One in ten CD8 + cells in the pancreas of living individuals with recent-onset type 1 diabetes recognizes the preproinsulin epitope PPI 15-24.

Rodriguez-Calvo T, Krogvold L, Amirian N, Dahl-Jørgensen K, von Herrath M.

May 1, 2021 J Autoimmun.

HLA class I hyper-expression unmasks beta cells but not alpha cells to the immune system in pre-diabetes.

Benkahla MA, Sabouri S, Kiosses WB, Rajendran S, Quesada-Masachs E, von Herrath MG.

May 1, 2021 Diabetologia.

Current and future therapies for type 1 diabetes.

von Scholten BJ, Kreiner FF, Gough SCL, von Herrath M.

Aug 13, 2021 Diabetes.

Multicomponent plasmid protects mice from spontaneous autoimmune diabetes.

Pagni PP, Chaplin J, Wijaranakula M, Wesley JD, Granger J, Cracraft J, O'Brien C, Perdue N, Kumar V, Li S, Ratliff SS, Roach A, Misquith A, Chan CL, Coppieters K, von Herrath M.

Aug 1, 2021 Curr Opin Endocrinol Diabetes Obes.

Current state of antigen-specific immunotherapy for type 1 diabetes.

Kreiner FF, von Scholten BJ, Coppieters K, von Herrath M.

Jul 11, 2021 Clin Transl Immunology.

Peripheral autoreactive CD8 T-cell frequencies are too variable to be a reliable predictor of disease progression of human type 1 diabetes.

Wesley JD, Pfeiffer S, Schneider D, Friedrich D, Perdue N, Sehested-Hansen B, Hagopian W, von Herrath MG.

Jun 16, 2021 Front Immunol.

Means, motive, and opportunity: do non-islet-reactive infiltrating T cells contribute to autoimmunity in type 1 diabetes?

Rodriguez-Calvo T, Christoffersson G, Bender C, von Herrath MG, Mallone R, Kent SC, James EA.

Sep 1, 2021 J Autoimmun.

IL-17 is expressed on beta and alpha cells of donors with type 1 and type 2 diabetes.

Rajendran S, Quesada-Masachs E, Zilberman S, Graef M, Kiosses WB, Chu T, Benkahla MA, Lee JM, von Herrath M.

Nov 2, 2021 Proc Natl Acad Sci U S A.

How benign autoimmunity becomes detrimental in type 1 diabetes.

von Herrath M, Bonifacio E.

Oct 20, 2021 Immune Matters

A cold case no longer

What happened when an LJI scientist revisited a diabetes mystery