Croft Lab
Michael Croft, Ph.D., and his team focus on a number of molecules that are members of the tumor necrosis factor (TNF) and tumor necrosis factor receptor (TNFR) family.
Disease Atopic Dermatitis
A leader in allergy research retires
LJI Professor Emeritus Toshiaki Kawakami, M.D., Ph.D., uncovered the molecular underpinnings of allergy, tumor responses, and more
LJI and Kyowa Kirin launch immunology fellowship program
New Michael Croft Fellowship in Immunology Fund to provide vital support for early career scientists
Lasting relief may be on the horizon for patients with atopic dermatitis
LJI research collaboration with Kyowa Kirin Co., Ltd., points to a novel approach to treat the most common form of eczema
T Cells
T cells are central to almost all immune responses. The CD4 subset is capable of directing B cell responses and humoral immunity, and can modulate the actions of many other cell types including CD8 T cells, dendritic cells, macrophages, eosinophils,…
Mouse Model of Atopic Dermatitis (AD)
As our knowledge of the FceRI-mediated signal transduction has grown for the last two decades, the need to study in vivo roles of this pathway in disease settings encouraged the Kawakami group to develop novel in vivo models of allergic…
T Cells
One large subgroup of these specialized T cells is encompassed by the IEL which are located in the epithelium of the small intestine in humans and mice. IEL are distinct from conventional T cells with regard to phenotype and function,…