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Allergies

Conditions such as eczema, contact dermatitis, allergy-induced asthma and hay fever are all connected to allergy.

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Alzheimer’s Disease

La Jolla Institute scientists are working to understand how the body's T cells may target the proteins involved in the plaques and tangles seen in brains with Alzheimer's disease.

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Asthma

Asthma affects more than 25 million people across the nation—7 million of them children—and the incidence is rising.

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Atherosclerosis

The underlying cause of many heart attacks is atherosclerosis, defined as build-up of deposits, or plaques, of cholesterol, calcium, and other substances in arteries.

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Atopic Dermatitis / Eczema

Atopic dermatitis occurs when a person’s immune system causes inflammation of the skin, which also makes the skin more vulnerable to environmental irritants and allergens.

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Cancer

Cancers all have one thing in common: mutated cells from one's own body begin to grow uncontrollably.

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CMV

CMV is the number one infectious cause of congenital birth defects worldwide. Researchers at La Jolla Institute are working to define the molecular underpinnings of CMV infection.

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COVID-19

The La Jolla Institute for Immunology is home to a multi-lab Coronavirus Taskforce that capitalizes on our competitive advantages of unique skill in infectious disease research, state-of-the-art technology, and highly collaborative organization.

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Dengue

Dengue fever is the world’s most common mosquito-borne disease, giving rise to 390 million cases of viral disease yearly in tropical regions of Africa, Latin America and Asia.

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Ebola

Ebola, which is endemic to west and central Africa, gives rise to hemorrhagic fever, vomiting, diarrhea, and muscle pain, and is almost always fatal.

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Fibrosis

Fibrosis occurs when immune cells mistakenly attack these connective tissues, causing the tissues to thicken and scar.

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Food Allergies

Allergens like egg, shellfish, or peanut proteins stimulate white blood cells to dump excessive quantities of immune molecules into the blood, triggering inflammation.

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HIV Vaccine

La Jolla Institute scientists are working to help develop an HIV/AIDS vaccine that can stimulate the immune system to neutralize many strains of the virus.

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Japanese Encephalitis

More than 3 billion people are at risk of Japanese encephalitis, a viral disease that sickens an estimated 68,000 people each year, killing up to 20,400.

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Lassa Fever

Lassa virus is endemic to West Africa and kills nearly 5,000 people a year. Research led by La Jolla Institute scientists lays the groundwork for anti-Lassa vaccine development.

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Lung Cancer

Lung cancer is the leading cause of cancer death for both men and women in the United States. Researchers at La Jolla Institute for Immunology are studying ways to halt lung cancer growth.

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Multiple Sclerosis

There is no cure for multiple sclerosis, but several La Jolla Institute investigators are exploring novel approaches to treat the disease.

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Nipah

Nipah virus is endemic to regions of Southeast Asia, India, and Bangladesh, and kills 40–70  percent of those infected.

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Strep Throat

Strep throat is one of a several conditions, among them pneumonia, scarlet fever, impetigo, and flesh-eating necrotizing fasciitis, caused by the bacterium Streptococcus pyogenes.

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Tuberculosis

Tuberculosis kills more people each year than any other infectious disease. Scientists at La Jolla Institute are working to help doctors treat those at most risk—sooner.

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Type 1 Diabetes

Type 1 diabetes accounts for up to 2 million U.S. cases and occurs when the immune system mistakenly destroys insulin-producing cells in the pancreas.

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Vaccines

Despite great advances in vaccine development, only 26 licensed vaccines currently exist worldwide. As a result, one out of every three deaths in the world today is the result of infectious disease.

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Vasculitis

Vasculitis is the umbrella term for nearly 20 rare diseases all associated with inflammation of the blood vessels.

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Whooping Cough

This extremely contagious disease is caused by the bacterium Bordetella pertussis, and it can be fatal in newborns.

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Yellow Fever

The yellow fever vaccine is one of vaccine biology’s great success stories. Scientists are hoping to learn how to design effective vaccines against other pathogens by studying the immune response induced by the yellow fever vaccine.

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Zika

The current Zika outbreak has been declared an international health emergency by the World Health Organization citing concerns that as many as four million people could be infected by the end of 2016.

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