Neurodegenerative Diseases
The aim of this work funded by Aligning Science Across Parkinson’s (ASAP), in collaboration with Dr. Alessandro Sette, is to
Tuberculosis
The aim of this work, in collaboration with Dr. Bjoern Peters, is to identify and characterize T cell epitopes from
Cancer Immunology
In 2013, Dr. Vijayanand teamed up with Professor Christian Ottensmeier at the Cancer Center, University of Southampton, UK, to
Role of T Cells in Viral Infections (Including SARS-CoV-2)
Selected References Kusnadi A, Ramírez-Suástegui C, Fajardo V, Chee SJ, Meckiff BJ, Simon H, Pelosi E, Seumois G, Ay
Role of T cell in allergy and Asthma
Selected References Grégory Seumois, Ciro Ramírez-Suástegui, Benjamin J. Schmiedel, Shu Liang, Bjoern Peters, Alessandro Sette, Vijayanand P (2020). Single-cell
Genetic basis of immune-mediated diseases
While an enormous number of genetic variants have been associated with risk for human disease, how these variants affect
Athlerosclerosis
ATHEROSCLEROSIS Working in collaboration with LJI Professor Klaus Ley, the Sette Lab aims to help develop vaccines that target inflammatory
Neuro-immune crosstalk in the pancreas during onset of type 1 diabetes
Team: Gustaf Christoffersson The histopathologic features of human type 1 diabetes are remarkably heterogeneous throughout the pancreas. One lobule of
Modeling and detection of viral infections in human pancreas slices
Team: Mehdi Benkahla It is thought that an interaction between predisposing genes and environmental factors, such as viral infections, may
Characterization of HLA class I expression in autoantibody positive and type 1 diabetic donors
Team: Mehdi Benkahla and Somayeh Sabouri Type 1 diabetes (T1D) is an autoimmune disease characterized by increased blood glucose levels
Detailed in-situ characterization of cytokines, immune and endocrine cell in the human pancreas
Team: Sakthi Rajendran, Estefania Quesada-Masachs, Christine Bender Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of
Characterization of in-situ IL17 expression in human pancreas
Team: Sakthi Rajendran, Estefania Quesada-Masachs and Mehdi Benkahla IL-17 is a pro-inflammatory cytokine important in shaping host immune responses against