The hidden science of allergy shots
LJI scientists study cockroach allergies to discover how allergy immunotherapies really work
Disease allergies
Vijayanand Lab
Pandurangan Vijayanand, M.D., Ph.D., and his lab members employ genomics tools to understand, diagnose and treat pulmonary disease such as asthma, lung cancer and infectious diseases, including the novel coronavirus.
Sette Lab
Alessandro Sette, Dr.Biol.Sci., defines in chemical terms the specific structures (epitopes) that the immune system recognizes and uses this knowledge to measure and understand immune responses.
Peters Lab
Bjoern Peters, Ph.D., and his lab members are focused on the development of computational tools to address fundamental questions in immunology.
A leader in allergy research retires
LJI Professor Emeritus Toshiaki Kawakami, M.D., Ph.D., uncovered the molecular underpinnings of allergy, tumor responses, and more
Stopping lung damage before it turns deadly
LJI scientists discover new drug target for severe asthma, fibrosis
Role of T cell in allergy and Asthma
Selected References Grégory Seumois, Ciro Ramírez-Suástegui, Benjamin J. Schmiedel, Shu Liang, Bjoern Peters, Alessandro Sette, Vijayanand P (2020). Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma. Science Immunology. 2020 Jun 12;5(48):eaba6087. doi: 10.1126 PMID: 32532832. PMCID:…
Allergy
Cockroach Allergy: The Sette lab is working to identify the sites on allergen molecules that trigger an inflammatory immune response. This effort includes research into cockroach allergy, which is a major contributor to asthma development in urban settings. As part…
PKCq
PKC enzymes play critical roles in the differentiation and proliferation of many cell types, including T cells, and in the response to diverse stimuli. Little is known, however, about the substrate specificity and role of individual PKC isoforms in distinct…