Exposure to common cold coronaviruses can teach the immune system to recognize SARS-CoV-2
Researchers caution: It is too soon to say whether pre-existing immune cell memory affects COVID-19 clinical outcomes
Disease COVID-19
La Jolla Institute for Immunology receives $1 million from GHR Foundation in support of COVID-19 research
LA JOLLA, CA – La Jolla Institute for Immunology (LJI) has announced a $1 million gift from GHR Foundation, an independent global philanthropy based in Minneapolis, MN. This significant gift will support the work of the Coronavirus Immunotherapy Consortium (CoVIC), a global partnership headquartered…
Do some people have protection against the coronavirus?
We’re now more than seven months into the coronavirus pandemic that has upended the lives of most of Earth’s inhabitants.
Can You Get COVID-19 Twice? Scientists Say It’s Too Early to Tell
Recovery from the virus seems to stimulate protective immunity, but there’s not enough data to determine how long that protection lasts.
Concerns about Waning COVID-19 Immunity Are Likely Overblown
The decline seen in some studies is normal, experts say. But scientists must wait to see whether infection confers long-term protection
SARS-COV-2
COVIC-DB: To co-run the LJI-led CoVIC database in the effort to find ideal therapeutic combinations for the novel coronavirus, the assays that best predict efficacy, and the features that provide protection. Coronavirus Immunotherapy Consortium (CoVIC) CoVIC Database Supported by the…
SARS-COV-2
Reactivity study: A collaboration between the Sette lab and Shane Crotty, Ph.D., to document acquired immunity to SARS-CoV-2 and help guide COVID-19 vaccine developers. Their May 2020 Cell study documents a robust antiviral immune response to SARS-CoV-2 in a group…
Designing Vaccines: Differentiation and Function of Follicular Helper CD4 T Cells (Tfh Cells)
A video lecture on Tfh cell biology can be seen here. Germinal centers are the critical sites for the development of long term humoral immunity in the form of antigen-specific memory B lymphocytes and long-lived plasma cells. CD4 T cells…
From Wuhan to San Diego—How a mutation on the novel coronavirus has come to dominate the globe
A small variation has made the novel coronavirus fitter—but not more deadly
Even in the worst COVID-19 cases, the body launches immune cells to fight back
International collaboration provides important piece of COVID-19 puzzle
What we can learn from SARS
Researchers comb through hundreds of studies to find clues to beating COVID-19
First detailed analysis of immune response to SARS-CoV-2 bodes well for COVID-19 vaccine development
Study finds robust antiviral T cell response in humans with COVID-19 and detects substantial crossreactivity in unexposed individuals; in a piece of good news provides a benchmark for testing of vaccine candidates.
LJI’s Erica Ollmann Saphire receives $100,000 Fast Grant for COVID-19 research
Antibody therapeutics will likely be a critical tool for protecting frontline healthcare workers and those at most risk of SARS-CoV-2 infection
LJI scientists awarded new funding to combat COVID-19
To aid vaccine design, researchers will investigate how a diverse population fights off viral attack
LJI scientists identify potential targets for immune responses to novel coronavirus
Their analysis provides essential information for vaccine design and the evaluation of diagnostics and vaccine candidates
