Sette Lab
Alessandro Sette, Dr.Biol.Sci., defines in chemical terms the specific structures (epitopes) that the immune system recognizes and uses this knowledge to measure and understand immune responses.
Disease Whooping Cough
Vac to the future
Vaccine researchers take on the challenge of predicting B. pertussis immunization outcomes
Asymptomatic infections may underlie recent rise in whooping cough
Surprising insights on pertussis vaccines pave the way for next-gen protection
Whooping Cough
Research to identify mechanisms and correlates of long-lasting vaccine-induced immunity to whooping cough. The lab aims to define transcriptional responses to vaccine boost from donors originally primed with aP vs. wP and identify cell types associated with differential responses, as…
Pertussis
Immunological Basis of Differences in Protection Between Pertussis Vaccines: The recent increase in cases of whooping cough among teenagers in the US suggests that the protection conferred by the acellular Bordetella pertussis vaccine (aP) that became standard in the mid…