Toxoplasma gondii HLA-B0702-restricted GRA7 (20-28) peptide with adjuvants and a universal helper T cell epitope elicits CD8(+) T cells prodicing interferon-γ and resuces parasite burden in HLA-B0702 mice

May 4, 2022 Nature.

Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs

Eschweiler S, Ramírez-Suástegui C, Li Y, King E, Chudley L, Thomas J, Wood O, von Witzleben A, Jeffrey D, McCann K, Simon H, Mondal M, Wang A, Dicker M, Lopez-Guadamillas E, Chou TF, Dobbs NA, Essame L, Acton G, Kelly F, Halbert G, Sacco JJ, Schache AG, Shaw R, McCaul JA, Paterson C, Davies JH, Brennan PA, Singh RP, Loadman PM, Wilson W, Hackshaw A, Seumois G, Okkenhaug K, Thomas GJ, Jones TM, Ay F, Friberg G, Kronenberg M, Vanhaesebroeck B, Vijayanand P, Ottensmeier CH.

Feb 25, 2022 Science Immunology

Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type–dependent effects of disease-risk variants

Benjamin J. Schmiedel,vCristian Gonzalez-Colin, Vicente Fajardo, Job Rocha, Ariel Madrigal, Ciro Ramirez-Suastegui, Sourya Bhattacharyya, Hayley Simon, Jason A. Greenbaum, Bjoern Peters, Gregory Seumois, Ferhat Ay, Vivek Chandra, Pandurangan, Vijayanand

Jan 14, 2022 Blood.

A congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.

Ludwig L, Lareau CA, Bao EL, Liu N, Utsugisawa T, Tseng AM, Myers SA, Verboon JM, Ulirsch JC, Luo W, Muus C, Fiorini C, Olive ME, Vockley CM, Munschauer M, Hunter A, Ogura H, Yamamoto T, Inada H, Nakagawa S, Ozono S, Subramanian V, Chiarle R, Glader B, Carr SA, Aryee MJ, Kundaje A, Orkin S, Regev A, McCavit T, Kanno H, Sankaran VG.

Toxoplasma gondii HLA-B*0702-restricted GRA7 (20-28) peptide with adjuvants and a universal helper T cell epitope elicits CD8(+) T cells prodicing interferon-γ and resuces parasite burden in HLA-B*0702 mice

Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs

Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type–dependent effects of disease-risk variants

A congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.

Toxoplasma gondii HLA-B0702-restricted GRA7 (20-28) peptide with adjuvants and a universal helper T cell epitope elicits CD8(+) T cells prodicing interferon-γ and resuces parasite burden in HLA-B0702 mice