Revelations
How sex-based differences shape the immune system—and what these discoveries mean for the future of medicine
Disease Asthma
Stopping asthma in its tracks
New therapeutic "cocktails" may provide long-lasting relief for treatment-resistant asthma and other immune system inflammatory diseases.
Vijayanand Lab
Pandurangan Vijayanand, M.D., Ph.D., and his lab members employ genomics tools to understand, diagnose and treat pulmonary disease such as asthma, lung cancer and infectious diseases, including the novel coronavirus.
Peters Lab
Bjoern Peters, Ph.D., and his lab members are focused on the development of computational tools to address fundamental questions in immunology.
Kronenberg Lab
Mitchell Kronenberg, Ph.D., and his team study T cells – white blood cells responsible for recognizing and responding to foreign invaders, such as microbes.
Croft Lab
Michael Croft, Ph.D., and his team focus on a number of molecules that are members of the tumor necrosis factor (TNF) and tumor necrosis factor receptor (TNFR) family.
Ay Lab
Ferhat Ay, Ph.D., works to understand gene regulation in complex organisms and diseases.
LJI home to new “Center of Excellence”
LJI's Flow Cytometry Core brings cutting-edge technology to immune system researchers
LJI and Kyowa Kirin launch immunology fellowship program
New Michael Croft Fellowship in Immunology Fund to provide vital support for early career scientists
Blocking immune system ‘messenger’ may treat severe asthma
Finally beating asthma might hinge on blocking HRF and IgE interactions
LJI researchers find missing piece of the asthma puzzle
New study reveals how the inflammatory "LIGHT" protein leads to airway remodeling and long-term breathing issues
Asthma researcher Sara Herrera de la Mata wins BioLegend Graduate Fellowship in Immunology
Herrera de la Mata aims to understand how asthma turns deadly
Stopping lung damage before it turns deadly
LJI scientists discover new drug target for severe asthma, fibrosis
Role of T cell in allergy and Asthma
Selected References Grégory Seumois, Ciro Ramírez-Suástegui, Benjamin J. Schmiedel, Shu Liang, Bjoern Peters, Alessandro Sette, Vijayanand P (2020). Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma. Science Immunology. 2020 Jun 12;5(48):eaba6087. doi: 10.1126 PMID: 32532832. PMCID:…
LJI asthma researcher Jermaine Khumalo receives AAI Intersect Fellowship
New fellowship will support data science and immunology cross-training in two pioneering LJI labs
Epigenetics
The Vijayanand lab has a strong interest in understanding the role of T cell enhancers (epigenetics players) in asthma, developing cutting-edge tools to study enhancer function, and utilizing these tools to understand the molecular basis of asthma. This includes…
New study points to a better way to ward off asthma triggers
LJI study suggests future asthma therapies need to target two key immune molecules
A step toward helping patients breathe deeply
LJI scientists track down a protein that may add to lung damage in asthma and related diseases
Allergic Diseases
Pediatric Milk Allergy: To study the frequency and phenotype of milk allergen-specific T cells in cohorts with different disease manifestations and define molecular markers of disease status and progression to tolerance. This research will contribute to developing improved and new…
T cell biology and Asthma
The Vijayanand lab employs genomic and epigenomic tools to understand the molecular basis of asthma, making key contributions in understanding the immunological basis of asthma, including identifying CCR4 as a key chemokine receptor that regulates recruitment of T cells…
Genetics of Human Diseases
While an enormous number of genetic variants have been associated with risk for human disease, how these variants affect gene expression in various cell types remains largely unknown. To address this gap as it relates to immune cells, as…
Structural Cells
Non-lymphoid structural cells of tissues are recipients of inflammatory signals from immune cells, but they also make inflammatory products that can affect the migration, localization, and activity of immune cells in the tissues. Together this contributes to the pathologic changes…
LJI scientists uncover immune cells that may lower airway allergy and asthma risk
Study opens up new path to research to fighting allergic diseases
Seqster Signs 3-year License Agreement of SRP™ to La Jolla Institute of Immunology for Asthma Study
Seqster research portal empowers study participants to instantly collect & share medical records and genomic data with researchers
