Revelations
How sex-based differences shape the immune system—and what these discoveries mean for the future of medicine
Disease Parkinson’s Disease
Immune cells may lead to more Parkinson’s cases in men
LJI scientists uncover autoimmune response that may help explain why Parkinson's disease is twice as common in male patients
Sette Lab
Alessandro Sette, Dr.Biol.Sci., defines in chemical terms the specific structures (epitopes) that the immune system recognizes and uses this knowledge to measure and understand immune responses.
Cecilia Lindestam Arlehamn wins WHAM Edge Award funding to study sex-based differences in Alzheimer’s and Parkinson’s diseases
Some neurological diseases show up more in men versus women. Researchers need to know why.
Scientists uncover new targets for treating Parkinson’s disease
LJI study suggests therapies could stop T cells from attacking brain cells in Parkinson's
Neurodegenerative Diseases
The aim of this work funded by Aligning Science Across Parkinson’s (ASAP), in collaboration with Dr. Alessandro Sette, is to investigate T cell reactivity and disease progression in Parkinson’s disease. We are also interested in characterizing T cell reactivity in…
Six LJI scientists named “Highly Cited Researchers”
The international recognition reflects how LJI research is valued by scientific peers
Inside the labs of three leading San Diego scientists
LJI Professors Shane Crotty, Ph.D., Bjoern Peters, Ph.D., and Alessandro Sette, Dr. Biol. Sci., were named “Highly Cited Researchers” this week by Clarivate.
LJI scientists receive $3.5 million to investigate role of immune cells in Parkinson’s disease
More than 930,000 Americans are living with Parkinson's disease
Parkinson’s
The lab investigates T cell reactivity and disease progression in Parkinson’s disease. Findings suggest immune cells are responsible for disease onset. Early interference with T cell responses could prevent the disease from manifesting itself or progressing. Selected References Lindestam Arlehamn…
LJI scientists link immune cells to Parkinson’s Disease onset
New research gives further evidence that autoimmunity plays a role in Parkinson’s disease
