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Apr 23, 2021 Immune Matters
Unmasking the pancreas

No one knows exactly what triggers type 1 diabetes, but researchers at La Jolla Institute for Immunology have uncovered some fascinating clues.

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Neuro-immune crosstalk in the pancreas during onset of type 1 diabetes

Team: Gustaf Christoffersson The histopathologic features of human type 1 diabetes are remarkably heterogeneous throughout the pancreas. One lobule of

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von Herrath
Modeling and detection of viral infections in human pancreas slices

Team: Mehdi Benkahla It is thought that an interaction between predisposing genes and environmental factors, such as viral infections, may

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Characterization of HLA class I expression in autoantibody positive and type 1 diabetic donors

Team: Mehdi Benkahla and Somayeh Sabouri Type 1 diabetes (T1D) is an autoimmune disease characterized by increased blood glucose levels

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Detailed in-situ characterization of cytokines, immune and endocrine cell in the human pancreas

Team: Sakthi Rajendran, Estefania Quesada-Masachs, Christine Bender Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of

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von Herrath
Characterization of in-situ IL17 expression in human pancreas

Team: Sakthi Rajendran, Estefania Quesada-Masachs and Mehdi Benkahla IL-17 is a pro-inflammatory cytokine important in shaping host immune responses against

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Expression of HLA class II in human pancreatic tissue sections

Team: Estefania Quesada-Masachs, Sakthi Rajendran Type 1 diabetes (T1D) is an autoimmune disease in which insulin-producing β cells are attacked

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Exploring toxic effects of T1D patient’s serum in pancreatic β cells

Team: Estefania Quesada-Masachs, Sakthi Rajendran Type 1 diabetes (T1D), an autoimmune disease that usually affects young people, is on the

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