Croft
T Cells

T cells are central to almost all immune responses. The CD4 subset is capable of directing B cell responses and

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Cheroutre
Regulation of mucosal immunity by stromal cells and dendritic cells crosstalk in the gut

Genetic regulation by vitamin A is involved in multiple biological processes such as embryonic development, vision, and immunity. To exert

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Cheroutre
The Contribution of Central and/or Peripheral Tolerance in Celiac Disease

Celiac Disease (CD) is an autoimmune-like inflammatory disease induced by aberrant immune responses initiated by MHC class II restricted CD4

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Cheroutre
Mucosal CD4- CD8- T Cells

One large subgroup of specialized T cells is encompassed by the intraepithelial T cells which are located in the epithelium

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Cheroutre
Role of Pre-TCR Signaling in Central Tolerance and Autoimmunity?

Autoimmunity is a self-destructive disease condition mediated mainly by pathogenic selfreactive αβ T cell receptor (TCR) expressing T lymphocytes. Self-tolerance

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Cheroutre
Mechanisms Involved in The Generation of High Affinity Effector Memory T Cells

A hallmark of immune memory is that repeated infections are met with accelerated or/and enhanced protective immunity. Furthermore, unlike naive

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Cheroutre
CD4+ Cytotoxic Lymphocytes

MHC class-II restricted CD4+ T cytotoxic cells (CD4 CTL) are among the best examples of extreme measures the immune system

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Cheroutre
T Cell Function

We are now trying to elucidate the regulatory functions displayed by the self-specific agonist selected T cells and their role

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Cheroutre
T Cells

One large subgroup of these specialized T cells is encompassed by the IEL which are located in the epithelium of

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Benedict
The Lymphotoxin-Interferon Antiviral Immunity Axis

Over the last 15 years our lab has been studying the link between lymphotoxins (LT) and the regulation of type

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Benedict
CMV Targets the Immune Checkpoint Inhibitor BTLA

Virulent isolates of CMV encode the ul144 orf, and we identified UL144 as an orthologue of the herpesvirus entry mediator

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Benedict
T Cell Immunity and CMV

HCMV-specific CD8 T cells protect bone marrow transplant patients when used in cellular immunotherapy, and their long-term maintenance is enhanced

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