Asthma researcher Sara Herrera de la Mata wins BioLegend Graduate Fellowship in Immunology

Aug 18, 2022 Behind the Science

Asthma researcher Sara Herrera de la Mata wins BioLegend Graduate Fellowship in Immunology

Herrera de la Mata aims to understand how asthma turns deadly

Feb 25, 2022 Science Immunology

Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type–dependent effects of disease-risk variants

Benjamin J. Schmiedel,vCristian Gonzalez-Colin, Vicente Fajardo, Job Rocha, Ariel Madrigal, Ciro Ramirez-Suastegui, Sourya Bhattacharyya, Hayley Simon, Jason A. Greenbaum, Bjoern Peters, Gregory Seumois, Ferhat Ay, Vivek Chandra, Pandurangan, Vijayanand

May 4, 2022 Research News

Investigating cancer drug toxicity leads to a critical discovery

LA JOLLA—It’s not often that a failed clinical trial leads to a scientific breakthrough. When patients in the UK started

Apr 12, 2022 Immune Matters

No patient overlooked

LJI postdoctoral research Jermaine Khumalo, Ph.D., has a new strategy for studying asthma.

Feb 25, 2022 Research News

LJI team uncovers new subsets of CD4+ ‘helper’ T cells

New analysis shows men and women really do have immune cell differences

Jan 1, 2021 Nat Genet.

Promoter-interacting expression quantitative trait loci are enriched for functional genetic variants.

Chandra V, Bhattacharyya S, Schmiedel BJ, Madrigal A, Gonzalez-Colin C, Fotsing S, Crinklaw A, Seumois G, Mohammadi P, Kronenberg M, Peters B, Ay F, Vijayanand P.

Feb 1, 2021 J Exp Med.

Modulating the quantity of HIV Env-specific CD4 T cell help promotes rare B cell responses in germinal centers.

Lee JH, Hu JK, Georgeson E, Nakao C, Groschel B, Dileepan T, Jenkins MK, Seumois G, Vijayanand P, Schief WR, Crotty S.

Jan 21, 2021 Sci Immunol.

Severely ill COVID-19 patients display impaired exhaustion features in SARS-CoV-2-reactive CD8+ T cells.

Kusnadi A, Ramírez-Suástegui C, Fajardo V, Chee SJ, Meckiff BJ, Simon H, Pelosi E, Seumois G, Ay F, Vijayanand P, Ottensmeier CH.

Apr 1, 2021 Genome Res.

Multi-cell type gene coexpression network analysis reveals coordinated interferon response and cross-cell type correlations in systemic lupus erythematosus.

Panwar B, Schmiedel BJ, Liang S, White B, Rodriguez E, Kalunian K, McKnight AJ, Soloff R, Seumois G, Vijayanand P, Ay F

Mar 15, 2021 J Immunol.

Functional analysis of immune signature genes in Th1* memory cells links ISOC1 and pyrimidine metabolism to IFN-g and IL-17 production.

Kushnareva Y, Mathews IT, Andreyev AY, Altay G, Lindestam Arlehamn CS, Pandurangan V, Nilsson R, Jain M, Sette A, Peters B, Sharma S.

Mar 4, 2021 Nat Commun.

Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure.

Murray MP, Engel I, Seumois G, Herrera-De la Mata S, Rosales SL, Sethi A, Logandha Ramamoorthy Premlal A, Seo GY, Greenbaum J, Vijayanand P, Scott-Browne JP, Kronenberg M.

May 1, 2021 J Allergy Clin Immunol.

PrecISE: precision medicine in severe asthma: An adaptive platform trial with biomarker ascertainment.

Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleecker ER, Cardet JC, Carr TF, Castro M, Cinelli A, Comhair SAA, Covar RA, Alexander LC, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Hoffman EA, Holguin F, Jackson DJ, Jain S, Jarjour NN, Ji Y, Kenyon NJ, Kosorok MR, Kraft M, Krishnan JA, Kumar R, Liu AH, Liu MC, Ly NP, Marquis MA, Martinez FD, Moy JN, O'Neal WK, Ortega VE, Peden DB, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Tulchinsky AF, Vijayanand P, Wechsler ME, Wenzel SE, White SR, Zeki AA, Ivanova A.