Publications

All      Ay      Benedict       Cheroutre       Croft       Crotty      Einav       Grifoni       Hogan       Kronenberg      Lisdestam Arlehamn      Myers      Peters      Rao      Reina      Saphire      Schmiedel      Schoenberger      Sette      Sharma      Shresta      Vijayanand      Weiskopf
Altman             Eschweiler      Hedrick       Kawakami      Ley      Pandurangan      Seumois      Von Herrath      
Nov 16, 2016
  • Nature Communications

17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells.

Schmiedel BJ, Seumois G, Samaniego-Castruita D, (…) Sette A, Peters B, Vijayanand P*.
May 12, 2023
  • Nat Commun

Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response.

Pagadala M, Sears TJ, Wu VH, Pérez-Guijarro E, Kim H, Castro A, Talwar JV, Gonzalez-Colin C, Cao S, Schmiedel BJ, Goudarzi S, Kirani D, Au J, Zhang T, Landi T, Salem RM, Morris GP, Harismendy O, Patel SP, Alexandrov LB, Mesirov JP, Zanetti M, Day CP, Fan CC, Thompson WK, Merlino G, Gutkind JS, Vijayanand P, Carter H.
Nov 29, 2018
  • Cell

Impact of genetic polymorphisms on human immune cell gene expression

Schmiedel BJ, Singh D, Madrigal A, Valdovino-Gonzalez AG, White BM, Zaperdiel-Gonzalo J, Ha B, Altay G, Greenbaum JA, McVicker G, Seumois G, Rao A, Kronenberg M, Peters B, Vijayanand P
Feb 25, 2022
  • Science Immunology

Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type–dependent effects of disease-risk variants

Benjamin J. Schmiedel,vCristian Gonzalez-Colin, Vicente Fajardo, Job Rocha, Ariel Madrigal, Ciro Ramirez-Suastegui, Sourya Bhattacharyya, Hayley Simon, Jason A. Greenbaum, Bjoern Peters, Gregory Seumois, Ferhat Ay, Vivek Chandra, Pandurangan, Vijayanand
Jan 19, 2018
  • Sci Immunol

Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis

Patil VS, Madrigal A, Schmiedel BJ, Clarke J, O’Rourke P, de Silva AD, Harris E, Peters B, Seumois G, Weiskopf D, Sette A, Vijayanand P
Nov 19, 2021
  • Nat Commun.

COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types.

Schmiedel BJ, Rocha J, Gonzalez-Colin C, Bhattacharyya S, Madrigal A, Ottensmeier CH, Ay F, Chandra V, Vijayanand P.
Apr 1, 2021
  • Genome Res.

Multi-cell type gene coexpression network analysis reveals coordinated interferon response and cross-cell type correlations in systemic lupus erythematosus.

Panwar B, Schmiedel BJ, Liang S, White B, Rodriguez E, Kalunian K, McKnight AJ, Soloff R, Seumois G, Vijayanand P, Ay F
Jun 12, 2020
  • Sci Immunol

Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma

Seumois G, Ramírez-Suástegui C, Schmiedel BJ, Liang S, Peters B, Sette A, Vijayanand P.
Nov 10, 2023
  • Sci Immunol

Transcriptomes and metabolism define mouse and human mait cell populations

Chandra S, Ascui G, Riffelmacher T, Chawla A, Ramirez-Suastegui C, Castelan VC, Seumois G, Simon H, Murray MP, Seo GY, Premlal ALR, Schmiedel B, Verstichel G, Li Y, Lin CH, Greenbaum J, Lamberti J, Murthy R, Nigro J, Cheroutre H, Ottensmeier CH, Hedrick SM, Lu LF, Vijayanand P, Kronenberg M
Mar 15, 2025
  • Nat Commun

Crohn’s disease-associated variant in laccase domain containing 1 (lacc1) modulates t cell gene expression, metabolism and t cell function

Li Y, Ascui G, Dicker M, Riffelmacher T, Chandra V, Schmiedel B, Chou TF, Vijayanand P, Kronenberg M
Mar 3, 2026

GPR25 promotes the formation of lung and liver tissue-resident memory CD8 T cells.

Feng H, Park S, Shin JW, Castañeda-Castro FE, Hernandez JR, Schmiedel BJ, Liu C, Jackson MR, Ottensmeier CH, Vijayanand P.
Jan 16, 2024
  • Nat Cancer.

Intra-tumoral T cells in pediatric brain tumors display clonal expansion and effector properties

Upadhye A, Meza Landeros KE, Ramírez-Suástegui C, Schmiedel BJ, Woo E, Chee SJ, Malicki D, Coufal NG, Gonda D, Levy ML, Greenbaum JA, Seumois G, Crawford J, Roberts WD, Schoenberger SP, Cheroutre H, Ottensmeier CH, Vijayanand P, Ganesan AP.