Publications

Jul 6, 2021 Nat Rev Immunol

Neutrophils in cancer: heterogeneous and multifaceted.

Hedrick CC, Malanchi I

Jun 4, 2021 J Leukoc Biol

The atypical small GTPase GEM/Kir is a negative regulator of the NADPH oxidase and NETs production through macroautophagy

Johnson JL, Ramadass M, Rahman F, Meneses-Salas E, Zgajnar NR, Carvalho Gontijo R, Zhang J, Kiosses WB, Zhu YP, Hedrick CC, Perego M, Gunton JE, Pestonjamasp K, Napolitano G, Catz SD.

Sep 29, 2020 Circulation

Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100-Reactive CD4(+) T-Regulatory Cells

Wolf D, Gerhardt T, Winkels H, Michel NA, Pramod AB, Ghosheh Y, Brunel S, Buscher K, Miller J, McArdle S, Baas L, Kobiyama K, Vassallo M, Ehinger E, Dileepan T, Ali A, Schell M, Mikulski Z, Sidler D, Kimura T, Sheng X, Horstmann H, Hansen S, Mitre LS, Stachon P, Hilgendorf I, Gaddis DE, Hedrick C, Benedict CA, Peters B, Zirlik A, Sette A, Ley K

Sep 8, 2020 J Immunother Cancer.

CyTOF mass cytometry reveals phenotypically distinct human blood neutrophil populations differentially correlated with melanoma stage.

Zhu YP, Eggert T, Araujo DJ, Vijayanand P, Ottensmeier CH, Hedrick CC.

Aug 18, 2020 Immunity

Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow

Dinh HQ, Eggert T, Meyer MA, Zhu YP, Olingy CE, Llewellyn R, Wu R, Hedrick CC.

Jul 24, 2020 Circulation

Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B 100-Reactive CD4 + T-Regulatory Cells

Jul 22, 2020 Sci Adv.

Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response.

Dhanwani R, Takahashi M, Mathews IT, Lenzi C, Romanov A, Watrous JD, Pieters B, Hedrick CC, Benedict CA, Linden J, Nilsson R, Jain M, Sharma S.

Jul 17, 2020 Circ Res

Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas

Zernecke A, Winkels H, Cochain C, Williams JW, Wolf D, Soehnlein O, Robbins CS, Monaco C, Park I, McNamara CA, Binder CJ, Cybulsky MI, Scipione CA, Hedrick CC, Galkina EV, Kyaw T, Ghosheh Y, Dinh HQ, Ley K.

Jun 1, 2020 J Leukoc Biol

Frontline Science: Kindlin-3 is essential for patrolling and phagocytosis functions of nonclassical monocytes during metastatic cancer surveillance

Marcovecchio PM, Zhu YP, Hanna RN, Dinh HQ, Tacke R, Wu R, McArdle S, Reynolds S, Araujo DJ, Ley K,Hedrick CC.

Mar 12, 2020 Nat Commun

Perivascular Localization of Macrophages in the Intestinal Mucosa Is Regulated by Nr4a1 and the Microbiome

Honda M, Surewaard BGJ, Watanabe M, Hedrick CC, Lee WY, Brown K, McCoy KD, Kubes P.

Mar 1, 2020 Mol Cancer Ther

Macrophage Syk-PI3Kγ Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk-PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression.

Joshi S, Liu KX, Zulcic M, Singh AR, Skola D, Glass CK, Sanders PD, Sharabi AB, Pham TV, Tamayo P, Shiang D, Dinh HQ, Hedrick CC, Morales GA, Garlich JR, Durden DL.

Jan 1, 2020 J Immunol

Patrolling Monocytes Control NK Cell Expression of Activating and Stimulatory Receptors to Curtail Lung Metastases

Narasimhan PB, Eggert T, Zhu YP, Marcovecchio P, Meyer MA, Wu R, Hedrick CC