Publications

Dec 1, 2021 J Immunol.

Thymus-derived CD4+CD8+ cells reside in mediastinal adipose tissue and the aortic arch.

Winkels H, Ghosheh Y, Kobiyama K, Kiosses WB, Orecchioni M, Ehinger E, Suryawanshi V, Herrera-De La Mata S, Marchovecchio P, Riffelmacher T, Thiault N, Kronenberg M, Wolf D, Seumois G, Vijayanand P, Ley K.

Nov 22, 2021 Cardiovasc Res.

Heterogeneity of immune cells in human atherosclerosis revealed by scRNA-Seq.

Vallejo J, Cochain C, Zernecke A, Ley K.

Nov 1, 2021 Mol Metab.

Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe(-/-) mice.

Leipner J, Dederichs TS, von Ehr A, Rauterberg S, Ehlert C, Merz J, Dufner B, Hoppe N, Krebs K, Heidt T, von Zur Muehlen C, Stachon P, Ley K, Wolf D, Zirlik A, Bode C, Hilgendorf I, Hardtner C.

Oct 26, 2021 mBio.

Endothelial heparan sulfate mediates hepatic neutrophil trafficking and injury during staphylococcus aureus sepsis.

Golden GJ, Toledo AG, Marki A, Sorrentino JT, Morris C, Riley RJ, Spliid C, Chen Q, Cornax I, Lewis NE, Varki N, Le D, Malmstrom J, Karlsson C, Ley K, Nizet V, Esko JD.

Aug 13, 2021 Nat Rev Immunol.

How the immune system shapes atherosclerosis: roles of innate and adaptive immunity.

Roy P, Orecchioni M, Ley K.

Aug 12, 2021 Front Cell Dev Biol.

Partial inhibition of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) enzyme in myeloid cells does not affect atherosclerosis.

Tillie R, De Bruijn J, Perales-Paton J, Temmerman L, Ghosheh Y, Van Kuijk K, Gijbels MJ, Carmeliet P, Ley K, Saez-Rodriguez J, Sluimer JC.

Aug 1, 2021 J Am Soc Nephrol.

Data-driven kidney transplant phenotyping as a histology-independent framework for biomarker discovery.

Buscher K, Heitplatz B, Van Marck V, Song J, Loismann S, Rixen R, Huchtmann B, Kurian S, Ehinger E, Wolf D, Ley K, Pavenstaedt H, Reuter S.

Jul 27, 2021 Cardiovasc Res.

Fortified tregs to fight atherosclerosis.

Ley K.

Jul 5, 2021 J Exp Med.

Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain.

Navia-Pelaez JM, Choi SH, Dos Santos Aggum Capettini L, Xia Y, Gonen A, Agatisa-Boyle C, Delay L, Goncalves Dos Santos G, Catroli GF, Kim J, Lu JW, Saylor B, Winkels H, Durant CP, Ghosheh Y, Beaton G, Ley K, Kufareva I, Corr M, Yaksh TL, Miller YI.

Jun 23, 2021 Nat Commun.

CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition.

Jung Y, Wen L, Altman A, Ley K.

May 31, 2021 Life (Basel).

Biomechanics of neutrophil tethers.

Cugno A, Marki A, Ley K.

May 14, 2021 Cells.

Inflammation and atherosclerosis.

Ley K.