» Publications

Sep 17, 2020 Blood

TET family dioxygenases and the TET activator vitamin C in immune responses and cancer

Yue, X, Rao A

Apr 6, 2020 Proc Natl Acad Sci U S A

Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells

Kim Y, Sundrud MS, Zhou C, Edenius M, Zocco D, Powers K, Zhang M, Mazitschek R, Rao A, Yeo CY, Noss EH, Brenner MB, Whitman M, Keller TL

Jan 16, 2020 Mol. Cell

HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells

Shukla V, Halabelian L, Balagere S, Samaniego-Castruita D, Feldman DE, Arrowsmith CH, Rao A, Aravind L.

Jan 1, 2020 J Biosci

TET methylcytosine oxidases: new insights from a decade of research

Lio CJ, Yue X, Lopez-Moyado IF, Tahiliani M, Aravind L, Rao A.

Sep 30, 2019 Nat Rev Immunol

Defining ‘T cell exhaustion’

Blank CU, Haining WN, Held W, Hogan PG, Kallies A, Lugil E, Lynn RC, Philip M, Rao A, Restifo NP, Schietinger A, Schumacher TN, Schwartzberg PL, Sharpe AH, Speiser DE, Wherry EJ, Youngblood BA, Zehn D

Sep 3, 2019 Biochemistry

Unusual activity of a Chlamydomonas TET/JBP family enzyme

Aravind L, Balasubramanian R, Rao A

Aug 29, 2019 Blood

Dysregulation of the TET family of epigenetic regulators in hematopoietic malignancies

Lio CJ, Yuita H, Rao A

Aug 20, 2019 Proc Natl Acad Sci U S A

Paradoxical association of TET loss of function with genome-wide DNA hypomethylation

Lopez-Moyado IF, Tsagaratou A, Yuita H, Seo H, Delatte B, Heinz S, Benner C, Rao A

Jul 1, 2019 Nat Struct Mol Biol

Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition

Halabelian L, Ravichandran M, Li Y, Zeng H, Rao A, Aravind L, Arrowsmith CH

Jun 18, 2019 Proc Natl Acad Sci U S A

TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion

Seo H, Chen J, González-Avalos E, Samaniego-Castruita D, Das A, Wang YH, López-Moyado IF, Georges RO, Zhang W, Onodera A, Wu CJ, Lu LF, Hogan PG, Bhandoola A, Rao A

May 14, 2019 Proc Natl Acad Sci U S A

Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor

Mognol GP, González-Avalos E, Ghosh S, Spreafico R, Gudlur A, Rao A, Damoiseaux R, Hogan PG

May 9, 2019 J Phys Chem C Nanomater Interfaces

DNA translocation through hybrid bilayer nanopores

Balasubramanian R, Pal S, Joshi H, Rao A, Naik A, Varma M, Chakraborty B, Maiti PK