Publications

Sep 14, 2021 Science

Low-dose mRNA-1273 COVID-19 vaccine generates durable memory enhanced by cross-reactive T cells

Mateus J, Dan JM, Zhang Z, Rydyznski Moderbacher C, Lammers M, Goodwin B, Sette A, Crotty S, Weiskopf D.

Jun 30, 2021 J Immunol

HLA-DR Marks recently divided antigen-specific effector CD4 T cells in active tuberculosis patients

Tippalagama R, Singhania A, Dubelko P, Lindestam Arlehamn CS, Crinklaw A, Pomaznoy M, Seumois G, deSilva AD, Premawansa S, Vidanagama D, Gunasena B, Goonawardhana NDS, Ariyaratne D, Scriba TJ, Gilman RH, Saito M, Taplitz R, Vijayanand P, Sette A, Peters B, Burel JG

Jun 22, 2021 Mucosal Immunol

Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates

Sakai S, Lora NE, Kauffman KD, Dorosky DE, Oh S, Namasivayam S, Gomez F, Fleegle JD; Tuberculosis Imaging Program, Arlehamn CSL, Sette A, Sher A, Freeman GJ, Via LE, Barry III CE, Barber DL

Jun 18, 2021 Sci Immunol

Activation of mTORC1 at late endosomes misdirects T cell fate decision in older individuals

Jin J, Kim C, Xia Q, Gould TM, Cao W, Zhang H, Li X, Weiskopf D, Grifoni A, Sette A, Weyand CM, Goronzy JJ

Jun 15, 2021 J Clin Invest

Relationship of SARS-CoV-2-specific CD4 response to COVID-19 severity and impact of HIV-1 and tuberculosis co-infection

Riou C, Du Bruyn E, Stek C, Daroowala R, Goliath RT, Abrahams F, Said-Hartley Q, Allwood BW, Hsiao NY, Wilkinson KA, Lindestam Arlehman CS, Sette A, Wasserman S, Wilkinson RJ

Jun 3, 2021 Cell

Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs

Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Gallagher KME, Bauer MR, Taylor HB, Dunn WA, Tarr C, Sidney J, Rachimi S, Conway HL, Katsis K, Wang Y, Leistritz-Edwards D, Durkin MR, Tomkins-Tinch CH, Finkel Y, Nachshon A, Gentili M, Rivera KD, Carulli IP, Chea VA, Chandrashekar A, Bozkus CC, Carrington M; MGH COVID-19 Collection & Processing Team, Bhardwaj N, Barouch DH, Sette A, Maus MV, Rice CM, Clauser KR, Keskin DB, Pregibon DC, Hacohen N, Carr SA, Abelin JG, Saeed M, Sabeti PC

May 21, 2021 Cell Host Microbe

SARS-CoV-2 huan T cell epitopes: adaptive immune response against COVID-19

Grifoni A, Sidney J, Vita R, Peters B, Crotty S, Weiskopf D, Sette A

May 5, 2021 J Am Chem Soc

Backbone modifications of HLA-A2-restricted antigens induce diverse binding and T cell activation outcoues

Gibadullin R, Randall CJ, Sidney J, Sette A, Gellman SH

Apr 23, 2021 Vaccines (Basel)

Balanced cellular and humoral immune responses targeting multiple antigens in adult receiving a quadrivalent inactivated influenza vaccine

Yu ED, Grifoni A, Sutherland A, Voic H, Wang E, Frazier A, Jimenez-Truque N, Yoder S, Welsh S, Wooden S, Koff W, Creech B, Sette A, da Silva Antunes R

Apr 21, 2021 J Am Chem Soc

Backbone Modifications of HLA-A2-Restricted Antigens Induce Diverse Binding and T Cell Activation Outcomes

Gibadullin, R., Randall, C.J., Sidney, J., Sette, A., and Gellman, S.H.

Apr 13, 2021 J Clin Invest

Tissue resident-like CD4+ T cells secreting IL-17 control Mycobacteria tuberculosis in the human lung

Ogongo P, Tezera LB, Ardain A, Nhamoyebonde S, Ramsuran D, Singh A, Ngoepe A, Karim F, Naidoo T, Khan K, Dullabh KJ, Fehlings M, Lee BH, Nardin A, Lindestam Arlehamn CS, Sette A, Behar SM, Steyn AJ, Madansein R, Kloverpris HN, Elkington PT, Leslie A

Apr 8, 2021 JCI Insight

A system-view of Bordetella pertussis booster vaccination responses in adults primed with whole-cell versus acellular vaccine in infancy

da Silva Antunes, R, Soldevila, F, Pomaznoy, M, Babor, M, Bennett, J, Tian, Y, Khalil, N., Qian, Y, Mandava, A, Scheuermann, RH, Cortese, M, Pulendran B, Petro CD, Gilkes, AP, Purcell LA, Sette A, and Peters B