Publications

Neutralizing ebolavirus: structural insights into the envelope glycoprotein and antibodies targeted against it.

Lee JE, Saphire EO.

An efficient platform for screening expression and crystallization of glycoproteins produced in human cells.

Lee JE, Fusco ML, Saphire EO.

Ebolavirus glycoprotein structure and mechanism of entry.

Lee JE, Saphire EO.

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor.

Lee JE, Fusco ML, Hessell AJ, Oswald WB, Burton DR, Saphire EO.

Complex of a protective antibody with its Ebola virus GP peptide epitope: unusual features of a V lambda x light chain.

Lee JE, Kuehne A, Abelson DM, Fusco ML, Hart MK, Saphire EO.

Structure of a high-affinity “mimotope” peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies.

Saphire EO, Montero M, Menendez A, van Houten NE, Irving MB, Pantophlet R, Zwick MB, Parren PW, Burton DR, Scott JK, Wilson IA.

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling.

Cárdenas WB, Loo YM, Gale M Jr, Hartman AL, Kimberlin CR, Martínez-Sobrido L, Saphire EO, Basler CF

The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12.

Scanlan CN, Pantophlet R, Wormald MR, Saphire EO, Calarese D, Stanfield R, Wilson IA, Katinger H, Dwek RA, Burton DR, Rudd PM.