Publications

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

He W, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee W, Yong P, Torres J, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Robers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R

Humoral and cellular immune memory to four COVID-19 vaccines

Zhang Z, Mateus J, Coelho CH, Dan JM, Rydyznski Moderbacher C, Galvez RI, Cortes FH, Grifoni A, Tarke A, Chang J, Excarrega EA, Kim C, Goodwin B, Bloom N, Frazier A, Weiskopf D, Sette A, Crotty S

Memory B cell development after asymptomatic or mile symptomatic SARS-CoV-2 infection

Kato Y, Bloom NI, Sun P, Balinsky CA, Qiu Q, Cheng Y, Jani V, Schilling MA, Goforth CW, Weir DL, Ramos I, Sealfon SC, Letizia AG, Crotty S

Development of a T cell-based immunodiagnostic system to effectively distinguish SARS-CoV-2 infection and COVID-19 vaccination status

Dawen Yu E, Wang E, Garrigan E, Goodwin B, Sutherland A, Chang J, Galvez R, Mateus J, Rawlings SA, Smith DM, Frazier A, Weiskopf D, Dan JM, Crotty S, Grifoni A, Sette A, da Silva Antunes R

SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron

Tarke A, Coelho C, Zhang Z, Dan JM, Dawen Yu E, Methot N, Bloom N, Goodwin B, Phillips E, Mallal S, Sidney J, Filaci G, Weiskopf D, da Silva Antunes R, Crotty S, Grifoni A, Sette A

From structure to sequence: Antibody discovery using cryoEM

Antanasijevic A, Bowman CA, Kirchdoerfer RN, Cottrell CA, Ozorowski G, Upadhyay AA, Cirelli KM, Carnathan DG, Enemuo CA, Sewall LM, Nogal B, Zhao F, Groschel B, Schief WR, Sok D, Silvestri G, Crotty S, Bosinger SE, Ward AB

Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2.

Rodrigues KA, Rodriguez-Aponte SA, Dalvie NC, Lee JH, Abraham W, Carnathan DG, Jimenez LE, Ngo JT, Chang JYH, Zhang Z, Yu J, Chang A, Nakao C, Goodwin B, Naranjo CA, Zhang L, Silva M, Barouch DH, Silvestri G, Crotty S, Love JC, Irvine DJ.

Phosphate-mediated co-anchoring of RBD immunogens and molecular adjuvants to alum 4 potentiates humoral immunity against SARS-CoV-2

Rodrigues KA, Rodriguez-Aponte SA, Dalvie NC, Lee JH, Abraham W, Carnathan DG, Jimenez LE, Ngo JT, Chang JYH, Zhang Z, Yu J, Chang A, Nakao C, Goodwin B, Naranjo CA, Zhang L, Silva M, Barouch DH, Silvestri G, Crotty S, Love C, Irvine DJ

A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity.

Silva M, Kato Y, Melo MB, Phung I, Freeman BL, Li Z, Roh K, Van Wijnbergen JW, Watkins H, Enemuo CA, Hartwell BL, Chang JYH, Xiao S, Rodrigues KA, Cirelli KM, Li N, Haupt S, Aung A, Cossette B, Abraham W, Kataria S, Bastidas R, Bhiman J, Linde C, Bloom NI, Groschel B, Georgeson E, Phelps N, Thomas A, Bals J, Carnathan DG, Lingwood D, Burton DR, Alter G, Padera TP, Belcher AM, Schief WR, Silvestri G, Ruprecht RM, Crotty S, Irvine DJ.

Revealing T follicular helper cells with BCL6.

Crotty S.