Publications

Jan 5, 2018 J Biol Chem

Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8

Matho MH, Schlossman A, Gilchuk IM, Miller G, Mikulski Z, Hupfer M, Wang J, Brita A, Meng X, Xiang Y, Kaever T, Doukov T, Ley K, Crotty S, Peters B, Hsieh-Wilson LC, Crowe JE Jr, Zajonc DM

Dec 14, 2017 Nature

Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours

Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath AW

Nov 21, 2017 Nat Commun

Structure-based design of naïve-like HIV-1 envelope trimers to silence non-renutralizing epitopes and eliminate CD4 binding

Kulp DW, Steichen JM, Pauthner M, Hu X, Schiffner T, Liguori A, Cottrell CA, Havenar-Daughton C, Ozorowski G, Georgeson E, Kalyuzhny O,Willis JR, Kubitz M, Adachi Y, Reiss SM, Shin M, de Val N, Ward AB, Crotty S, Burton DR, Schief WR

Oct 24, 2017 PLoS One

Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells

Reiss S, Baxter AE, Cirelli KM, Dan JM, Morou A, Daigneault A, Brassard N, Silvestri G, Routy JP, Havenar-Daughton C, Crotty S, Kaufmann DE

Aug 20, 2017 J Neuroimmunol

Absence of the neurogenesis-dependent nuclear receptor TLX induces inflammation in the hippocampus

Kozareva DA, Hueston CM, O'Léime CS, Crotty S, Dockery P, Cryan JF, Nolan YM

Aug 1, 2017 Antiviral Res

Development of an animal model of progressive vaccinia in nu/nu mice and the use of bioluminescence imaging for assessment of the efficacy of monoclonal antibodies against vaccinial B5 and L1 proteins

Zaitseva M, Thomas A, Meseda CA, Cheung CYK, Diaz CG, Xiang Y, Crotty S, Golding H

Aug 1, 2017 Curr Opin Immunol

Germinal center enhancement by extended antigen availability

Cirelli KM, Crotty S

Jul 11, 2017 Proc Natl Acad Sci USA

A distinct subpopulation of CD25- T-follicular regulatory cells localizes in the germinal centers

Wing JB, Kitagawa Y, Locci M, Hume H, Tay C, Morita T, Kidani Y, Matsuda K, Inoue T, Kurosaki T, Crotty S, Coban C, Ohkura N, Sakaguchi S

Jun 20, 2017 Immunity

Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunication using optimized approaches

Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, McCoy LE, Oom AL, Ozorowski G, Post KW, Sharma SK, Steichen JM, de Taeye SW, Tokatlian T, Torrents de la Peña A, Butera ST, LaBranche CC, Montefiori DC, Silvestri G, Wilson IA, Irvine DJ, Sanders RW, Schief WR, Ward AB, Wyatt RT, Barouch DH, Crotty S, Burton DR

May 1, 2017 Nat Immunol

Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation

Yu B, Zhang K, Milner JJ, Toma C, Chen R, Scott-Browne JP, Pereira RM, Crotty S, Chang JT, Pipkin ME, Wang W, Goldrath AW

Apr 3, 2017 J Clin Invest

T cells control the generation of nanomolar-affinity anti-glycan antibodies

Polonskaya Z, Deng S, Sarkar A, Kain L, Comellas-Aragones M, McKay CS, Kaczanowska K, Holt M, McBride R, Palomo V, Self KM, Taylor S, Irimia A, Mehta SR, Dan JM, Brigger M, Crotty S, Schoenberger SP, Paulson JC, Wilson IA, Savage PB, Finn MG, Teyton L

Jan 31, 2017 J Virol

Adjuvanting an simian immunodeficiency virus vaccine with toll-like receptor ligands encapsulated in nanoparticles induces persistent antibody responses and enhanced protection in TRIM5α restrictive macaques

Katsuri SP, Kozlowski PA, Nakaya HI, Burger MC, Russo P, Pham M, Kovalenkov Y, Silveira EL, Havenar-Daughton C, Burton SL, Kilgore KM, Johnson MJ, Nabi R, Legere T, Sher ZJ, Chen X, Amara RR, Hunter E, Bosinger SE, Spearman P, Crotty S, Villinger F, Derdeyn CA, Wrammert J, Pulendran B