When regulatory T cells go bad
LJI and Augusta University scientists investigate link between "deprogrammed" regulatory T cells and cardiovascular disease
Disease Atherosclerosis
Haywire T cells attack protein in “bad” cholesterol
LJI research reveals how aggressive T cells can make heart disease even worse
Macrophages in the artery wall ‘smell’ their surroundings
Immune cells can sniff out octanal in blood, triggering dangerous inflammation and atherosclerosis
Six LJI scientists named “Highly Cited Researchers”
The international recognition reflects how LJI research is valued by scientific peers
Learning from men. Learning from women.
Men and women have different immune systems. With a better understanding of sex-specific immune differences, scientists can more effectively fight infections, cancers, heart disease, and even pregnancy complications.
The Conrad Prebys Foundation grants more than $450,000 for studies into childhood cancer, cardiovascular disease
New funding will support high-risk, high-reward projects led by two early-career scientists
Athlerosclerosis
ATHEROSCLEROSIS Working in collaboration with LJI Professor Klaus Ley, the Sette Lab aims to help develop vaccines that target inflammatory factors as a means to reduce atherosclerotic plaque formation. The researchers have identified several peptides suitable for vaccinating humans. The…
T cells can shift from helping to harming in atherosclerosis
LJI study brings scientists closer to designing a safe anti-atherosclerosis vaccine
Atherosclerosis Vaccine
Inflammation in Atherosclerosis
CD8 T Cell Functions in Atherosclerosis
Regulation of Treg Function in Cardiovascular Disease
iMAP of human atherosclerosis shortlisted for £30m research prize
The proposed iMAP will reveal new targets for immunotherapy, and may lead to a new wave of medicines and vaccines that can prevent heart attacks and strokes; La Jolla Institute for Immunology researcher Klaus Ley and Scripps researcher Eric Topol are key members of the iMAP team.