Kawakami
IgE Heterogeneity

Since their finding of ‘monomeric IgE effects’ on mast cell survival in 2001, Dr. Kawakami and associates have shown that

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Kawakami
Phospholipase C (PLC)-B3-Mediated Regulation of Stat5 Activity

Given their previous studies on crosstalks between PTKs-dependent and G protein-coupled receptor-dependent signals in FceRI-stimulated mast cells, they have been

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Kawakami
Mouse Model of Atopic Dermatitis (AD)

As our knowledge of the FceRI-mediated signal transduction has grown for the last two decades, the need to study in

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Kawakami
Btk-Mediated Regulation of Cytokine Production

During the course of the above-mentioned study, they found interactions between Btk and protein kinase C (PKC)-b and terreic acid

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Kawakami
Bruton’s Tyrosine Kinase (Btk) in Mast Cell Activation

Dr. Kawakami has been using the high-affinity IgE receptor (FceRI) signaling in mast cells as a model system. Following his

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Hedrick
Regulation of Treg Function in Cardiovascular Disease

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Hedrick
Epigenetic Regulation of Neutrophil and Monocyte Development in Disease

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Hedrick
Immunoprofiling of Human Immune Cells in Cardiovascular Disease and Cancer

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Hedrick
CD8 T Cell Functions in Atherosclerosis

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Crotty
HIV Vaccine Research (AIDS Vaccine Research)

Broadly neutralizing antibodies have been discovered in ~5% of HIV+ individuals. Some of those antibodies (HIV bnAbs) are capable of

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Crotty
Designing Vaccines: Differentiation and Function of Follicular Helper CD4 T Cells (Tfh Cells)

A video lecture on Tfh cell biology can be seen here. Germinal centers are the critical sites for the development

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Croft
Structural Cells

Non-lymphoid structural cells of tissues are recipients of inflammatory signals from immune cells, but they also make inflammatory products that

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