Publications

Jun 25, 2021 EMBO J.

Calcium signals regulate the functional differentiation of thymic iNKT cells.

Zhao M, Quintana A, Zhang C, Andreyev AY, Kiosses W, Kuwana T, Murphy A, Hogan PG, Kronenberg M

Jun 24, 2021 Nat Immunol

Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy

Eschweiler S, Clarke J, Ramírez-Suástegui C, Panwar B, Madrigal A, Chee SJ, Karydis I, Woo E, Alzetani A, Elsheikh S, Hanley CJ, Thomas GJ, Friedmann PS, Sanchez-Elsner T, Ay F, Ottensmeier CH, Vijayanand P

Jun 23, 2021 Nat Commun

CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition

Jung Y, Wen L, Altman A and Ley K

Jun 22, 2021 Mucosal Immunol

Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates

Sakai S, Lora NE, Kauffman KD, Dorosky DE, Oh S, Namasivayam S, Gomez F, Fleegle JD; Tuberculosis Imaging Program, Arlehamn CSL, Sette A, Sher A, Freeman GJ, Via LE, Barry III CE, Barber DL

Jun 18, 2021 Sci Immunol

Activation of mTORC1 at late endosomes misdirects T cell fate decision in older individuals

Jin J, Kim C, Xia Q, Gould TM, Cao W, Zhang H, Li X, Weiskopf D, Grifoni A, Sette A, Weyand CM, Goronzy JJ

Jun 16, 2021 Viruses

Emergence of a Novel Dengue Virus 3 (DENV-3) Genotype-I Coincident with Increased DENV-3 Cases in Yangon, Myanmar between 2017 and 2019

Soe AM, Ngwe Tun MM, Nabeshima T, Myat TW, Htun MM, Lin H, Hom NS, Inoue S, Nwe KM, Aye LPP, Fukuta M, Thant KZ, Hasebe F, Morita K, Shresta S, Thu HM, Moi ML

Jun 15, 2021 J Clin Invest

Relationship of SARS-CoV-2-specific CD4 response to COVID-19 severity and impact of HIV-1 and tuberculosis co-infection

Riou C, Du Bruyn E, Stek C, Daroowala R, Goliath RT, Abrahams F, Said-Hartley Q, Allwood BW, Hsiao NY, Wilkinson KA, Lindestam Arlehman CS, Sette A, Wasserman S, Wilkinson RJ

Jun 11, 2021 EBioMedicine

AI-guided discovery of the invariant host response to viral pandemics

Sahoo D, Katkar GD, Khandelwal S, Behroozikhah M, Claire A, Castillo V, Tindle C, Fuller M, Taheri S, Rogers TF, Beutler N, Ramirez SI, Rawlings SA, Pretorius V, Smith DM, Burton DR, Crotty Alexander LE, Duran J, Crotty S, Dan JM, Das S, Ghosh P

Jun 4, 2021 J Leukoc Biol

The atypical small GTPase GEM/Kir is a negative regulator of the NADPH oxidase and NETs production through macroautophagy

Johnson JL, Ramadass M, Rahman F, Meneses-Salas E, Zgajnar NR, Carvalho Gontijo R, Zhang J, Kiosses WB, Zhu YP, Hedrick CC, Perego M, Gunton JE, Pestonjamasp K, Napolitano G, Catz SD.

Jun 3, 2021 Cell

Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs

Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Gallagher KME, Bauer MR, Taylor HB, Dunn WA, Tarr C, Sidney J, Rachimi S, Conway HL, Katsis K, Wang Y, Leistritz-Edwards D, Durkin MR, Tomkins-Tinch CH, Finkel Y, Nachshon A, Gentili M, Rivera KD, Carulli IP, Chea VA, Chandrashekar A, Bozkus CC, Carrington M; MGH COVID-19 Collection & Processing Team, Bhardwaj N, Barouch DH, Sette A, Maus MV, Rice CM, Clauser KR, Keskin DB, Pregibon DC, Hacohen N, Carr SA, Abelin JG, Saeed M, Sabeti PC

Jun 2, 2021 J Am Soc Nephrol

Data Driven Kidney Transplant Phenotyping as a Histology-independent Framework for Biomarker Discovery

Buscher K, Heitplatz B, Van Marck V, Song J, Loismann S, Rixen R, Huchtmann B, Kurian S, Ehinger E, Wolf D, Ley K, Pavenstaedt H and Reuter S

Jun 1, 2021 J Allergy Clin Immunol

Combination blockade of OX40L and CD30L inhibits allergen-driven memory TH2 cell reactivity and lung inflammation

Gracias DT, Sethi GS, Mehta AK, Miki H, Gupta RK, Yagita H and Croft M