Publications

Nov 29, 2018 Cell

Impact of genetic polymorphisms on human immune cell gene expression

Schmiedel BJ, Singh D, Madrigal A, Valdovino-Gonzalez AG, White BM, Zaperdiel-Gonzalo J, Ha B, Altay G, Greenbaum JA, McVicker G, Seumois G, Rao A, Kronenberg M, Peters B, Vijayanand P

Oct 1, 2018 Oncogene

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity

Yu OM, Benitez JA, Plouffe SW, Ryback D, Klein A, Smith J, Greenbaum J, Delatte B, Rao A, Guan KL, Furnari FB, Chaim OM, Miyamoto S, Brown JH

Aug 23, 2018 Blood

Single cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

Shepherd MS, Li J, Wilson NK, Oedekoven CA, Li J, Belmonte M, Fink J, Prick JCM, Pask DC, Hamilton TL, L_ffler D, Rao A, Schroeder T, G_ttgens B, Green AR, Kent DG

Jul 9, 2018 Nat Commun

TCR signal strength controls thymic differentiation of iNKT cell subsets

Tuttle KD, Krovi SH, Zhang J, Bedel R, Harmacek L, Peterson LK, Dragone LL, Lefferts A, Halluszczak C, Riemondy K, Hesselberth JR, Rao A, O'Connor BP, Marrack P, Scott-Browne J, Gapin L

Oct 2, 2017 Nat Commun

NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia

Märklin M, Heitmann JS, Fuchs AR, Truckenmüller FM, Gutknecht M, Bugl S, Saur SJ, Lazarus J, Kohlhofer U, Quintanilla-Martinez L, Rammensee HG, Salih HR, Kopp HG, Haap M, Kirschniak A, Kanz L, Rao A, Wirths S, Müller MR

Oct 1, 2017 Curr Opin Genet Dev

TET proteins in natural and induced differentiation

Scott-Browne JP, Lio CJ, Rao A

Sep 1, 2017 J Leukoc Biol

Transcriptional and epigenetic regulation of T cell hyporesponsiveness

Pereira RM, Hogan PG, Rao A, Martinex GJ

Aug 15, 2017 Cell Rep

TET2 regulates mast cell differentiation and proliferation through catalytic and non-catalytic activities

Montagner S, Leoni C, Emming S, Della Chiara G, Balestrieri C, Barozzi I, Piccolo V, Togher S, Ko M, Rao A, Natoli G, Monticelli S

Aug 1, 2017 J Clin Invest

Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis

Zang S, Li J, Yang H, Zeng H, Han W, Zhang J, Lee M, Moczygemba M, Isgandarova S, Yang Y, Zhou Y, Rao A, You MJ, Sun D, Huang Y

Jul 1, 2017 Nat Genet

Lineage-specific functions of TET1 in the postimplantation mouse embryo

Khoueiry R, Sohni A, Thienpont B, Luo X, Velde JV, Bartoccetti M, Boeckx B, Zwijsen A, Rao A, Lambrechts D, Koh KP

Jul 1, 2017 Nat Immunol

The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection

Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW

Apr 28, 2017 Exp Mol Med

TET family dioxygenases and DNA demethylation in stem cells and cancers

An J, Rao A, Ko M