Inside the labs of three leading San Diego scientists
LA JOLLA—Studying the immune system means venturing into uncharted territory, leading explorations of the countless immune cells and genetic players
Fighting Zika? Call in the T cells
LA JOLLA—Where Aedes mosquitoes fly, Zika virus may not be far behind. Although the explosive 2015–2016 Zika epidemics in the
Shresta Lab
Sujan Shresta,
Ph.D.
Associate Professor
Center for Infectious Disease and Vaccine Research
Sujan Shresta, Ph.D., and her team study the immunology and virology of mosquito-borne human pathogens such as dengue virus and Zika virus.
Sette Lab
Alessandro Sette,
Dr.Biol.Sci.
Professor
Center for Autoimmunity and Inflammation, Center for Infectious Disease and Vaccine Research
Alessandro Sette, Dr. Biol. Sci., defines in chemical terms the specific structures (epitopes) that the immune system recognizes and uses this knowledge to measure and understand immune responses.
Fighting Mosquito-Borne Viruses Requires a Precise Balance of Immune Cells
LA JOLLA—Every year, more than 68,000 people end up with a clinical case of Japanese encephalitis. One in four of
Q&A with Alessandro Sette, Dr. Biol. Sci.
Raised in Rome, Italy, in a family of lawyers, Dr. Sette started his science career as a young boy in
Q&A with Sujan Shresta
Thanks to climate change, very little now stands in the way of dengue and Zika virus continuing to spread outside
Maternally-acquired Zika immunity can increase dengue disease severity in mouse pups
LA JOLLA, CA—To say that the immune system is complex is an understatement: an immune response protective in one context
Global immunoprofiling effort reveals multifunctional T cell response during Zika infection
LA JOLLA, CA—When a massive Zika virus outbreak swept through South and Central America and the Caribbean in 2016, thousands
Maternal dengue immunity protects against fetal damage in mice following Zika virus infection
LA JOLLA, CA—Dengue and Zika viruses are closely related and carried by mosquitos. In infested subtropical and tropical areas, dengue