Inside the labs of three leading San Diego scientists
LA JOLLA—Studying the immune system means venturing into uncharted territory, leading explorations of the countless immune cells and genetic players
Fighting Zika? Call in the T cells
LA JOLLA—Where Aedes mosquitoes fly, Zika virus may not be far behind. Although the explosive 2015–2016 Zika epidemics in the
Emergence of Mosquito-Borne Viruses Such as DENV and ZIKV in Nepal
Development of Vaccines Against DENV and ZIKV
Adaptive Immune Response to DENV and ZIKV
Vaccine development for DENV is challenging in that the vaccine must induce long-lasting immunity against all four DENV serotypes (DENV1-4),
Innate Immune Response to DENV and ZIKV
The IFN system is a major mechanism by which many viruses evade the cellular antiviral response. DENV and ZIKV can
Shresta Lab
Sujan Shresta,
Ph.D.
Associate Professor
Center for Infectious Disease and Vaccine Research
Sujan Shresta, Ph.D., and her team study the immunology and virology of mosquito-borne human pathogens such as dengue virus and Zika virus.
Sette Lab
Alessandro Sette,
Dr.Biol.Sci.
Professor
Center for Autoimmunity and Inflammation, Center for Infectious Disease and Vaccine Research
Alessandro Sette, Dr. Biol. Sci., defines in chemical terms the specific structures (epitopes) that the immune system recognizes and uses this knowledge to measure and understand immune responses.
Fighting Mosquito-Borne Viruses Requires a Precise Balance of Immune Cells
LA JOLLA—Every year, more than 68,000 people end up with a clinical case of Japanese encephalitis. One in four of
Q&A with Alessandro Sette, Dr. Biol. Sci.
Raised in Rome, Italy, in a family of lawyers, Dr. Sette started his science career as a young boy in
Q&A with Sujan Shresta
Thanks to climate change, very little now stands in the way of dengue and Zika virus continuing to spread outside
