Revelations
How sex-based differences shape the immune system—and what these discoveries mean for the future of medicine
How sex-based differences shape the immune system—and what these discoveries mean for the future of medicine

LJI and UC San Diego scientists make striking discovery as they work to combat Zika and related viral threats

LJI scientists find protective T cells in children who experience two or more dengue virus infections

LJI Professor Sujan Shresta, Ph.D., is a leader in dengue virus research and vaccine development

Shresta and her LJI colleagues work toward pandemic preparedness as members of the national 'ReVAMPP' network

Sujan Shresta, Ph.D., and her team study the immunology and virology of mosquito-borne human pathogens such as dengue virus and Zika virus.

Alessandro Sette, Dr.Biol.Sci., defines in chemical terms the specific structures (epitopes) that the immune system recognizes and uses this knowledge to measure and understand immune responses.

Prebys Foundation celebrates ground-breaking female researchers

San Diego scientists work with business experts to advance dengue and Zika virus vaccine strategy

Sette has led investigations into the T cell response to SARS-CoV-2, tuberculosis, and more

Elong Ngono, Ph.D., accepted to Global Virus Network Rising Star Mentorship Program

LJI scientists uncover major clue toward developing a pan-flavivirus therapy

Men and women have different immune systems. With a better understanding of sex-specific immune differences, scientists can more effectively fight infections, cancers, heart disease, and even pregnancy complications.
Speaking up for science
The bioinformatics tools Dr. Peters has developed are invaluable for immunologists worldwide.
The Sette lab’s previous large scale epitope identification efforts (supported by HHS contracts) have led to a deeper understanding of the role of T cells and HLA variants in the development of (or protection from) DENV disease. Current efforts (supported…
The aim of this work, in collaboration with Bjoern Peters, Ph.D., and Pandurangan Vijayanand, M.D., Ph.D., is to characterize the immune response to dengue virus (DENV) and Mycobacterium tuberculosis (MTB), both of which represent major global health challenges. Specifically, the…

Future vaccines will need to harness the power of T cells in preventing Zika fever and Japanese encephalitis

The finding is important to both the basic understanding of this disease—the world’s most common mosquito-borne illness—and to the hunt for an effective vaccine for dengue.

LJI team finds that ‘doublet’ immune cells are much more common—and more important in disease—than previously thought

The fellowship specifically supports interdisciplinary training to encourage understanding between immunology researchers and computational scientists