Disease Dengue

Shresta Lab

Sujan Shresta, Ph.D., and her team study the immunology and virology of mosquito-borne human pathogens such as dengue virus and Zika virus.

Sette Lab

Alessandro Sette, Dr.Biol.Sci., defines in chemical terms the specific structures (epitopes) that the immune system recognizes and uses this knowledge to measure and understand immune responses.

Dengue Virus

The Sette lab’s previous large scale epitope identification efforts (supported by HHS contracts) have led to a deeper understanding of the role of T cells and HLA variants in the development of (or protection from) DENV disease. Current efforts (supported…

Human Immune Profiling Consortium

The aim of this work, in collaboration with Bjoern Peters, Ph.D., and Pandurangan Vijayanand, M.D., Ph.D., is to characterize the immune response to dengue virus (DENV) and Mycobacterium tuberculosis (MTB), both of which represent major global health challenges. Specifically, the…