Revelations

How sex-based differences shape the immune system—and what these discoveries mean for the future of medicine
The Sette lab’s previous large scale epitope identification efforts (supported by HHS contracts) have led to a deeper understanding of the role of T cells and HLA variants in the development of (or protection from) DENV disease. Current efforts (supported…
The aim of this work, in collaboration with Bjoern Peters, Ph.D., and Pandurangan Vijayanand, M.D., Ph.D., is to characterize the immune response to dengue virus (DENV) and Mycobacterium tuberculosis (MTB), both of which represent major global health challenges. Specifically, the…