Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response.
The Lymphotoxin-Interferon Antiviral Immunity Axis
Over the last 15 years our lab has been studying the link between lymphotoxins (LT) and the regulation of type
CMV Targets the Immune Checkpoint Inhibitor BTLA
Virulent isolates of CMV encode the ul144 orf, and we identified UL144 as an orthologue of the herpesvirus entry mediator
T Cell Immunity and CMV
HCMV-specific CD8 T cells protect bone marrow transplant patients when used in cellular immunotherapy, and their long-term maintenance is enhanced
CMV Interfaces with The Trail Cytokine System
We have recently discovered a novel connection between the TNF-related apoptosis inducing ligand (TRAIL) cytokine system and CMV. TRAIL is

Know Your Enemies
They help us digest food, balance our immune system, and keep our hearts and brains healthy. But harmful viruses and