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Nov 19, 2020 In the News

Covid- 19 – Good news on immunity

After infection or vaccination immunity to the virus may be long lasting

Nov 19, 2020 Institute News

Inside the labs of three leading San Diego scientists

LA JOLLA—Studying the immune system means venturing into uncharted territory, leading explorations of the countless immune cells and genetic players

Nov 18, 2020 In the News

The End of the Pandemic Is Now in Sight

A year of scientific uncertainty is over. Two vaccines look like they will work, and more should follow.

Oct 2, 2020 Science

Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

Mateus J, Grifoni A, Tarke A, Sidney J, Ramirez SI, Dan JM, Burger ZC, Rawlings SA, Smith DM, Phillips E, Mallal S, Lammers M, Rubiro P, Quiambao L, Sutherland A, Yu ED, da Silva Antunes R, Greenbaum J, Frazier A, Markmann AJ, Premkumar L, de Silva A, Peters B, Crotty S, Sette A and Weiskopf D

Jul 1, 2020 SSRN

Single-Cell Transcriptomic Analysis of SARS-CoV-2 Reactive CD4 + T Cells

Meckiff BJ, Ramírez-Suástegui C, Fajardo V, Chee SJ, Kusnadi A, Simon H, Grifoni A, Pelosi E, Weiskopf D, Sette A, Ay F, Seumois G, Ottensmeier C, Vijayanand P.

Aug 27, 2020 Front Neurosci

T cell responses to neural autoantigens are similar in Alzheimer’s disease patients and age-matched healthy controls

Dhanwani R, Sulzer D, Sette A, Lindestam Arlehamn CS

Oct 3, 2020 Mov Disord

Inflammation in experimental models of a-synucleinopathies

Harms AS, Kordower JH, Sette A, Lindestam Arlehamn CS, Sulzer D, Mach RH

Oct 9, 2020 Clin Infect Dis

Interferon-gama release assay for accurate detection of SARS-CoV-2 T cell response

Murugesan K, Jagannathan P, Pham TD, Pandey S, Bonilla HF, Jacobson K, Parsonnet J, Andrews JR, Weiskopf D, Sette A, Pinsky BA, Singh U, Banaei N

Oct 2, 2020 Cell

Key parameters of tumor epitope immunogenicity revealed through a consortium approach improve neoantigen prediction

Wells DK, van Buuren MM, Dang KK, Hubbard-Lucey VM, Sheehan KCF, Campbell KM, Lamb A, Ward JP, Sidney J, Blazquez AB, Rech AJ, Zaretsky JM, Comin-Anduix B, Ng AHC, Chour W, Yu TV, Rizvi H, Chen JM, Manning P, Steiner GM, Doan XC; Tumor Neoantigen Selection Alliance, Merghoub T, Guinney J, Kolom A, Selinsky C, Ribas A, Hellmann MD, Hacohen N, Sette A, Heath JR, Bhardwaj N, Ramsdell F, Schreiber RD, Schumacher TN, Kvistborg P, Defanoux NA

Sep 29, 2020 Proc Natl Acad Sci

Lack of evidence for BCG vaccine protection from severe COVID-19

Lindestam Arlehamn CS, Sette A, Peters B

Sep 28, 2020 Cytokine

Lack of evidence supporting a role of IFN-b and TGF-b iin differential polarization of Bordetella pertussis specific-T cell responses

da Silva Antunes R, Quiambao LG, Soldevila F, Sutherland A, Peters B, Sette A

Jul 16, 2020 Mucosal Immunol

Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial oad and disease severity in human tuberculosis

Du Bruyn E, Ruzive S, Lindestam Arlehamn CS, Sette A, Sher A, Barber DL, Wilkinson RJ, Riou C