LJI Professor Alessandro Sette elected to the American Academy of Microbiology

Mar 2, 2023 Institute News

LJI Professor Alessandro Sette elected to the American Academy of Microbiology

Sette has led investigations into the T cell response to SARS-CoV-2, tuberculosis, and more

Jan 1, 2022 Methods Mol Biol

Detection of α-synuclein-specific T cells in Parkinson’s disease

Dhanwani R, Sette A, Lindestam Arlehamn CS

Sep 22, 2022 Nat Immunol

Memory CD8+ T cell diversity and B cell responses correlate with protection against SARS-CoV-2 following mRNA vaccination

Brasu N, Elia I, Russo V, Montacchiesi G, Stabile SA, De Intinis C, Fesi F, Gizzi K, Macagno M, Montone M, Mussolin B, Grifoni A, Faravelli S, Marchese S, Forneris F, De Francesco R, Sette A, Barnaba V, Sottile A, Sapino A, Pace L

Sep 23, 2022 Blood

Hybrid immunity in immunocompromised patients with CLL after SARS-CoV-2 infection followed by booster mRNA vaccination

Lisa B, Gao Y, Wullimann D, Murén Ingelman-Sundberg H, Muschiol S, Healy K, Bogdanovic G, Pin E, Nilsson P, Kjellander C, Grifoni A, Sette A, Sällberg Chen M, Ljunggren HG, Buggert M, Hansson L, Osterborg A

Sep 15, 2022 bioRxiv

IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

Nelson CE, Foreman TW, Kauffman KD, Sakai S, Gould ST, Fleegle JD, Gomez F, NIAID/DIR Tuberculosis Imaging Program, Le Nouën C, Liu X, Burdette TL, Garza NL, Lafont BAP, Brooks K, Arlehamn CSL, Weiskopf D, Sette A, Hickman HD, Buchholz UJ, Johnson RF, Brenchley JM, Via LE, Barber DL

Sep 23, 2022 iScience

Asymptomatic or symptomatic SARS-CoV-2 infection plus vaccination confers increased adaptive immunity to variants of concern

Sun P, Ramos I, Coelho CH, Grifoni A, Balinsky CA, Vangeti S, Tarke A, Bloom NI, Jani V, Jakubski SJ, Boulifard DA, Cooper E, Goforth CW, Marayag J, Marrone A, Nunez E, White L, Porter CK, Sugiharto VA, Schilling M, Mahajan AS, Beckett C, Sette A, Sealfon SC, Crotty S, Letizia AG

Jul 15, 2022 Front Immunol

Specific CD4+ T cell responses to ancestral SARS-CoV-2 in children increase with age and show cross-reactivity to beta variant

Paul K, Sibbertsen F, Weiskopf D, Lütgehetmann M, Barroso M, Danecka MK, Glau L, Hecher L, Hermann K, Kohl A, Oh J, Schulze Zur Wiesch J, Sette A, Tolosa E, Vettorazzi E, Woidy M, Zapf A, Zazara DE, Mir TS, Muntau AC, Gersting SW, Dunay GA

Aug 5, 2022 Sciene

A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes

Bousbaine D, Fisch LI, London M, Bhagchandani P, Rezende de Castro TB, Mimee M, Olesen S, Reis BS, VanInsberghe D, Bortolatto J, Poyet M, Cheloha RW, Sidney J, Ling J, Gupta A, Lu TK, Sette A, Alm EJ, Moon JJ, Victora GD, Mucida D, Ploegh HL, Bilate AM

Sep 14, 2022 Cell Host Microbe

Immunological memory to common cold coronaviruses assessed longitudinally over a three-year period pre-COVID19 pandemic

Yu ED, Narowski TM, Wang E, Garrigan E, Mateus J, Frazier A, Weiskopf D, Grifoni A, Premkumar L, da Silva Antunes R, Sette A

Oct 3, 2022 J Clin Invest

NVX-CoV2373 vaccination induces functional SARS-CoV-2-specific CD4+ and CD8+ T cell responses

Rydyznski Moderbacher C, Kim CJ, Mateus J, Plested JS, Zhu M, Cloney-Clark S, Weiskopf D, Sette A, Fries L, Glenn G, Crotty S

Aug 10, 2022 Sci Transl Med

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty, S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R

Aug 9, 2022 Clin Transl Immunology

High-resolution analysis of individual spike peptide-specific CD4+ T-cell responses in vaccine recipients and COVID-19 patients.

Karsten H, Cords L, Westphal T, Knapp M, Brehm TT, Hermanussen L, Omansen TF, Schmiedel S, Woost R, Ditt V, Peine S, Lütgehetmann M, Huber S, Ackermann C, Wittner M, Addo MM, Sette A, Sidney J, Schulze Zur Wiesch J