A zika virus mutation enhances transmission potential and confers escape from protective dengue virus immunity.

Apr 12, 2022 Cell Rep

A zika virus mutation enhances transmission potential and confers escape from protective dengue virus immunity.

Regla-Nava JA, Wang YT, Fontes-Garfias CR, Liu Y, Syed T, Susantono M, Gonzalez A, Viramontes KM, Verma SK, Kim K, Landeras-Bueno S, Huang CT, Prigozhin DM, Gleeson JG, Terskikh AV, Shi PY, Shresta S.

May 9, 2022 Pathogens

Acute-phase serum cytokine levels and correlation with clinical outcomes in children and adults with primary and secondary dengue virus infection in Myanmar between 2017 and 2019.

Nwe KM, Ngwe Tun MM, Myat TW, Sheng Ng CF, Htun MM, Lin H, Hom NS, Soe AM, Elong Ngono A, Hamano S, Morita K, Thant KZ, Shresta S, Thu HM, Moi ML.

Sep 12, 2022 Nat Commun

SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus.

Branche E, Wang YT, Viramontes KM, Valls Cuevas JM, Xie J, Ana-Sosa-Batiz F, Shafee N, Duttke SH, McMillan RE, Clark AE, Nguyen MN, Garretson AF, Crames JJ, Spann NJ, Zhu Z, Rich JN, Spector DH, Benner C, Shresta S, Carlin AF.

Dec 12, 2022 Institute News

LJI Instructor Annie Elong Ngono, Ph.D., wins GVN support to advance infectious disease research

LA JOLLA—As an infectious disease researcher at La Jolla Institute for Immunology (LJI) Instructor Annie Elong Ngono, Ph.D., has spearheaded

Oct 17, 2022 Immune Matters

Online exclusive: The dengue problem

Researchers set out to develop a dengue virus vaccine 80 years ago. We still don't have a good one.

Sep 12, 2022 Research News

How human cells become Zika virus factories

LA JOLLA, CA—Zika virus has a trick up its sleeve. Once inside the body, the virus likes to make a

Jul 28, 2022

The life of a scientist studying Zika and dengue

Inside the work of immunologist Julia Timis

Jan 1, 2021 Am J Trop Med Hyg.

Whole genome sequencing of dengue virus serotype 2 from two clinical isolates and serological profile of dengue in the 2015-2016 Nepal outbreak.

Manandhar KD, McCauley M, Gupta BP, Kurmi R, Adhikari A, Nguyen AV, Elong Ngono A, Zompi S, Sessions OM, Shresta S.

Jan 29, 2021 PLoS Pathog.

Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice.

Wells AI, Grimes KA, Kim K, Branche E, Bakkenist CJ, DePas WH, Shresta S, Coyne CB.

Jan 11, 2021 JCI Insight.

Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade.

Nair S, Mazzoccoli L, Jash A, Govero J, Bais SS, Hu T, Fontes-Garfias CR, Shan C, Okada H, Shresta S, Rich JN, Shi PY, Diamond MS, Chheda MG.

May 5, 2021 Sci Rep.

Repeated exposure to dengue virus elicits robust cross neutralizing antibodies against Zika virus in residents of Northeastern Thailand.

Hattakam S, Elong Ngono A, McCauley M, Shresta S, Yamabhai M.

Jun 16, 2021 Viruses.

Emergence of a novel dengue virus 3 (DENV-3) genotype-I coincident with increased DENV-3 cases in Yangon, Myanmar between 2017 and 2019.

Soe AM, Ngwe Tun MM, Nabeshima T, Myat TW, Htun MM, Lin H, Hom NS, Inoue S, Nwe KM, Aye LPP, Fukuta M, Thant KZ, Hasebe F, Morita K, Shresta S, Thu HM, Moi ML.