When your body turns against you

For reasons not yet understood, autoimmune disorders are on the rise, from type 1 diabetes and multiple sclerosis to lupus and rheumatoid arthritis. The numbers are staggering: 1 in 12 Americans and 1 in 9 women will develop an autoimmune disorder. Most autoimmune diseases are caused when malfunctioning T cells start attacking the body’s own tissues. La Jolla Institute Professor Dr. Michael Croft, one of the world’s foremost experts on T cell biology, discusses the latest insights into what happens when the immune system goes rogue, as well as, ongoing efforts to treat and prevent autoimmunity.