Role of TCTP in cell biological and disease processes.
Histamine-Releasing Factor, a New Therapeutic Target in Allergic Diseases
Anaphylactic or tolerant outcomes with IgE
Anaphylactic or tolerant outcomes with IgE.
Recent advances in mast cell activation and regulation.
IgE Heterogeneity
Since their finding of ‘monomeric IgE effects’ on mast cell survival in 2001, Dr. Kawakami and associates have shown that
Phospholipase C (PLC)-B3-Mediated Regulation of Stat5 Activity
Given their previous studies on crosstalks between PTKs-dependent and G protein-coupled receptor-dependent signals in FceRI-stimulated mast cells, they have been
Mouse Model of Atopic Dermatitis (AD)
As our knowledge of the FceRI-mediated signal transduction has grown for the last two decades, the need to study in
Btk-Mediated Regulation of Cytokine Production
During the course of the above-mentioned study, they found interactions between Btk and protein kinase C (PKC)-b and terreic acid
Bruton’s Tyrosine Kinase (Btk) in Mast Cell Activation
Dr. Kawakami has been using the high-affinity IgE receptor (FceRI) signaling in mast cells as a model system. Following his