Scientists who aren’t virologists or vaccinologists can still make crucial contributions to the global effort to battle SARS-CoV-2.
Molecular Mechanisms Underlying Novel Interferonopathies
In addition to their protective role against microbial pathogens and neoplastic cells, high levels of circulating type I Interferon are
Targeting Tumor Endothelium for Cancer Surveillance and Immunotherapy
Preliminary data from our lab shows that vascular endothelial cells (vECs) mount remarkably potent innate responses to cell-free DNA, which
New Molecular Players in the cGAS-STING Pathway of Anti-Viral and Anti-Tumor Defense
Cell-free, immuno-stimulatory DNA is recognized in the cytoplasm of cells as a universal danger signal by the innate immune system.