Men and women have different immune systems. With a better understanding of sex-specific immune differences, scientists can more effectively fight infections, cancers, heart disease, and even pregnancy complications.
Molecular Mechanisms Underlying Novel Interferonopathies
In addition to their protective role against microbial pathogens and neoplastic cells, high levels of circulating type I Interferon are
Targeting Tumor Endothelium for Cancer Surveillance and Immunotherapy
Preliminary data from our lab shows that vascular endothelial cells (vECs) mount remarkably potent innate responses to cell-free DNA, which
New Molecular Players in the cGAS-STING Pathway of Anti-Viral and Anti-Tumor Defense
Cell-free, immuno-stimulatory DNA is recognized in the cytoplasm of cells as a universal danger signal by the innate immune system.