LJI researchers reveal how to undermine immune cell mobilization in allergic inflammation.
LA JOLLA, CA—Innate lymphoid cells (ILCs) are a type of white blood cell. Rather than recirculating constantly through the body,
Novel genomic tools provide new insight into human immune system
LA JOLLA, CA—When the body is under attack from pathogens, the immune system marshals a diverse collection of immune cells
LJI researchers discover key driver of atopic dermatitis
LA JOLLA, CA—Severe eczema, also known as atopic dermatitis, is a chronic inflammatory skin condition that is driven by an
One in a million
LA JOLLA, CA—The development of a vaccine that protects against HIV infections has proven extraordinarily difficult. One of the reasons
LJI researchers report how T cells navigate the rough-and-tumble environment of the bloodstream
LA JOLLA, CA—To eradicate pathogens or counteract inflammation, cells of the immune system move through often rapid blood flow toward
Allergy amplifier implicated in asthma also intensifies food allergy
LA JOLLA, CA—Almost eight percent of children under three years old and four percent of adults suffer food allergies, which
Dengue immunity can protect against Zika virus
LA JOLLA, CA—Manifestations of Zika virus (ZIKV) infection differ drastically. Sometimes they are catastrophic, most notably when they cause microcephaly
Tuberculosis and the microbiome
Mycobacterium tuberculosis stubbornly tops the list of the world’s biggest infectious killers and, for decades, has successfully evaded all efforts to
Tethered to the wall
Neutrophils, the immune system’s EMTs, spend most of their lives racing through the bloodstream constantly on the lookout for bacteria
Taking a closer look
Hypothesis-driven research is at the heart of scientific endeavors. But just as often as confirming current ideas, experimental observations can
Accounting for human diversity
Traditionally, researchers have relied on genetically identical mouse strains to gain insight into the complex world of human diseases while
No longer lost in translation
LA JOLLA, CA—Mouse models have advanced our understanding of immune function and disease in many ways but they have failed