Jul 1, 2013 Nature
An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry
Sharma S, Quintana A, Findlay GM, Mettlen M, Baust B, Jain M, Nilsson R, Rao A, Hogan PG
Jul 1, 2013 Immunity
The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunigy
Wang Y, Stanford SM, Zhou W, Curtsinger JM, Mikulski Z, Shaheen ZR, Cheng G, Sawatzke K, Campbell AM, Auger JL, Bilgic H, Shoyama FM, Schmeling DO, Balfour HH Jr, Hasegawa K, Chan AC, Corbett JA, Binstadt BA, Mescher MF, Ley K, Bottini N, Peterson EJ
Jul 1, 2013 PLoS Biology
Production of α-galactosylceramide by a prominent member of the human gut microbiota
Wieland Brown LC, Penaranda C, Kashyap PC, Williams BB, Clardy J, Kronenberg M, Sonneburg JL, Comstock LE, Bluestone JA, Fischbach MA
Jun 2, 2013 PLoS One
Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: immunologic effects and efficacy in NOD mice
Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, Nepom G, Ehlers M, Staeva T, Garren H, Steinman L, Chan AC, von Herrath M
Jun 1, 2013 Current Opinion in Immunology
Dynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cells
Choi YS, Yang JA, Crotty S
Jun 1, 2013 Journal of Medicinal Chemistry
A potent and selective small-molecure inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases
He Y, Liu S, Menon A, Stanford S, Oppong E, Gunawan AM, Wu L, Wu DJ, Barrios AM, Bottini N, Cato AC, Zhang ZY
Jun 1, 2013 Current Opinion in Virology
Modulation of SAP dependent T:B cell interactions as a strategy to improve vaccination
Hu J, Havenar-Daughton C, Crotty S
Jun 1, 2013 Nature Immunology
Intrahepatic meyloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection
Huang LR, Wohlleber D, Reisinger F, Jenne CN, Cheng RL, Abdullah Z, Schildberg FA, Odenthal M, Dienes HP, van Rooijen N, Schmitt E, Garbi N, Croft M, Kurts C, Kubes P, Protzer U, Heikenwalder M, Knolle PA
Jun 1, 2013 Nature Immunology
A ‘GEM’ of a cell
Kronenberg M, Zajonc DM
Jun 1, 2013 Proceedings of the National Academy of Sciences of the United States of America
Regulation of T cell function by the ubiquitin-specific protease USP9X via modulating the Carma1-Bcl10-Malt1 complex
Park Y, Jin HS, Liu YC
Jun 1, 2013 Nature Reveiws Molecular Cell Biology
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
Pastor WA, Aravind L, Rao A
Jun 1, 2013 Science Translational Medicine
Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8+ T cells in type 1 diabetes
Roep BO, Solvason N, Gottlieb PA, Abreu JR, Harrison LC, Eisenbarth GS, Yu L, Leviten M, Hagoplan WA, Buse JB, von Herrath M, Quan J, King RS, Robinson WH, Utz PJ, Garren H, BHT-3021 Investigators, Steinman L