LA JOLLA—Scientists at La Jolla Institute for Immunology (LJI) have received a new grant of more than $2.3 million from the National
In 2013, Dr. Vijayanand teamed up with Professor Christian Ottensmeier at the Cancer Center, University of Southampton, UK, to
Targeting Tumor Endothelium for Cancer Surveillance and Immunotherapy
Preliminary data from our lab shows that vascular endothelial cells (vECs) mount remarkably potent innate responses to cell-free DNA, which
New Molecular Players in the cGAS-STING Pathway of Anti-Viral and Anti-Tumor Defense
Cell-free, immuno-stimulatory DNA is recognized in the cytoplasm of cells as a universal danger signal by the innate immune system.
Immunotherapies for head and neck cancer: To develop new cancer therapies by studying how the immune system, by way of
Immunoprofiling of Human Immune Cells in Cardiovascular Disease and Cancer
CD4+ Cytotoxic Lymphocytes
MHC class-II restricted CD4+ T cytotoxic cells (CD4 CTL) are among the best examples of extreme measures the immune system
A Novel CTLA4-Mediated Treg Cell-Intrinsic Signaling Pathway
Recent work by others has provided evidence that, in contrast to conventional T cells, PKCq negatively regulates the suppressive activity
Pandurangan Vijayanand, M.D., Ph.D., and his lab members employ genomics tools to understand, diagnose and treat pulmonary disease such as asthma, lung cancer and infectious diseases, including the novel coronavirus.
Sonia Sharma, Ph.D., and her lab members lead unbiased, genome-scale approaches to unravel innate immunity, the body’s early immune response to microbial pathogens and neoplastic cells.